Results 221 to 230 of about 9,895,443 (300)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A large-scale benchmark dataset for Urdu script optical character recognition with systematic augmentation. [PDF]

Data Brief
Yasir F, Kazmi M, Qazi SA.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Oxidative Stress Induced Senescent Macrophage-Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming. [PDF]

Aging Cell
Wang S, Mu J, Zhao W, Hu C, Shi X, Zhou H, Liu J, Wu F.   +7 more
europepmc   +1 more source

Assessing realism of artificial intelligence-generated colorectal polyp images: International multicenter blinded reader study. [PDF]

Endosc Int Open
Sodmann P, Weber R, Wettstein V, Kafetzis I, Chiang Y, Parayitam V, Pauletti M, Kouladouros K, Meining A, Hann A.   +9 more
europepmc   +1 more source

Correction: TSP50 facilitates breast cancer stem cell‑like properties maintenance and epithelial‑mesenchymal transition via PI3K p110α mediated activation of AKT signaling pathway. [PDF]

J Exp Clin Cancer Res
Gao F, Liu S, Wang J, Wei G, Yu C, Zheng L, Sun L, Wang G, Sun Y, Bao Y, Song Z.   +10 more
europepmc   +1 more source

Spinal Intradural Extramedullary Schwannomas Mimicking Intramedullary Tumors: A Case Series. [PDF]

Cureus
Katase S, Ogiu R, Tsuchiya K, Gomyo M, Konishi K, Hosogane N, Yokoyama K.   +6 more
europepmc   +1 more source

Computer-aided detection of equivocal spinal tuberculosis on X-ray using a YOLOv11-based deep learning model. [PDF]

Front Public Health
Yuan Y, Ma J, Ma H, Zhang M, Qiu X, Shen L, Ren Z, Wang J, Abulizi A, Hu W, Nijiati M.   +10 more
europepmc   +1 more source