Results 131 to 140 of about 3,018,272 (257)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Photon-counting CT: image quality evaluation in patients with tibial plateau fracture treated with metallic osteosynthesis material. [PDF]

Eur Radiol Exp
Björkman AS, Malusek A, Persson A, Gauffin H, Koskinen SK.   +4 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Synthesis of Amyloid Images Using a Generative Adversarial Network from 2-Dimensional ¹⁸F-FDG Images and Evaluation for Clinical Use. [PDF]

J Nucl Med Technol
Honda M, Yamada T, Watanabe S, Watanabe A, Nagaoka T, Nemoto M, Mikami K, Hanaoka K, Kaida H, Handa H, Ishii K, Kimura Y.   +11 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Surgeon interpretation of margin status utilizing intraoperative 3D tomosynthesis during breast-conserving surgery. [PDF]

Breast Cancer Res Treat
Leonard LD, Cohen E, Perry R, Sun J, Ehlers R, Refinetti A, Johnson HM, Akay C, Colen JS, DeSnyder S, Fallahian F, Hwang R, Hunt KK, Wu Y, Tamirisa N.   +14 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A method for tissue-mask supported whole-body image registration in the UK Biobank. [PDF]

Sci Rep
Utkueri Y, Lundström E, Ahlström H, Öfverstedt J, Kullberg J.   +4 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

See the small lesions: Frequency-guided spatial debiasing GAN for multimodal medical image fusion. [PDF]

iScience
Zhou T, Wang J, Lu H, Zhang M, Zhang Z, Yu H, Zheng P.   +6 more
europepmc   +1 more source