Results 51 to 60 of about 311,604 (269)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The role of 99mTc-Ubiquicidin (UBI) and 99mTc-IgG scintigraphies in diagnosis of acute appendicitis: A preliminary result [PDF]

open access: yes, 2014
Introduction: Appendicitis is one of the most common surgical emergencies. In spite of the relatively high rate of negative appendectomy, as a result of miss diagnosis, uncertainty of diagnosis still continues to challenge physicians.
Assadi, M.   +6 more
core  

A Rare Case of Hip Pain Secondary to Pigmented Villonodular Synovitis [PDF]

open access: yes, 2020
A 19-year-old Asian male presented to our emergency department with atraumatic right hip pain radiating to the right groin associated with pain on ambulation.
Ganguly, Bhaskar   +4 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Images in Emergency Medicine: Pediatric Spinal Cord Injury Without Radiographic Abnormality

open access: greenWestern Journal of Emergency Medicine, 2008
Silman, Eric F   +3 more
doaj   +2 more sources

Deep learning in Emergency Medicine: Recent contributions and methodological challenges

open access: yesEmergency Care Journal, 2020
In the last few years, artificial intelligence (AI) technology has grown dramatically impacting several fields of human knowledge and medicine in particular.
Francesco Faita
doaj   +1 more source

48-year-old with Coronavirus Disease 2019 [PDF]

open access: yes, 2020
Case Presentation: A 48-year-old male who presented with signs and symptoms suggestive of an upper respiratory infection was seen at an urgent care, he had a negative chest radiograph and was discharged.
Finn, Ryan M.   +2 more
core  

Improving dialysis adherence for high risk patients using automated messaging: Proof of concept [PDF]

open access: yes, 2017
Comorbidities and socioeconomic barriers often limit patient adherence and self-management with hemodialysis. Missed sessions, often associated with communication barriers, can result in emergency dialysis and avoidable hospitalizations.
An, T.   +6 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Operating bedside cardiac ultrasound program in emergency medicine residency: A retrospective observation study from the perspective of performance improvement.

open access: yesPLoS ONE, 2021
BackgroundPoint-of-care ultrasound is one of useful diagnostic tools in emergency medicine practice and considerably depends on physician's performance.
Ki Hong Kim   +4 more
doaj   +1 more source

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