Results 61 to 70 of about 81,344 (281)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Custom, Contract, and Kidney Exchange [PDF]

open access: yes, 2012
In this Essay, we examine a case in which the organizational and logistical demands of a novel form of organ exchange (the nonsimultaneous, extended, altruistic donor (NEAD) chain) do not map cleanly onto standard cultural schemas for either market or ...
Healy, Kieran, Krawiec, Kimberly D.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Afterlives of the Californian Ideology| Building Blockchain Frontiers: Ethereum as an Extension of the Californian Ideology

open access: yesInternational Journal of Communication, 2023
The Ethereum blockchain has emerged as a new technology with particular affordances that lend themselves to entrepreneurial visions aligned with the Californian Ideology.
Ann Brody   +2 more
doaj   +2 more sources

Imaginaris del retorn a la Colòmbia postconflicte. Discursos de colombians refugiats a l’Equador

open access: yesDigithum, 2017
Aquest article es proposa d’identificar els imaginaris del retorn dels colombians refugiats a l’Equador i ho fa mitjançant descriure’n les trajectòries migratòries i les condicions sota les quals aquestes persones, que van deixar el país per causes ...
Felipe Andrés Aliaga Sáez   +4 more
doaj   +1 more source

Nation Branding and Policy transfer: Insights from Norden. EL-CSID Working Paper Issue 2018/22 • October 2018 [PDF]

open access: yes, 2018
Recent years have seen an interesting development in practices and policies of nation branding. Alongside an emphasis in which nation branding programmes seek to activate desires of conspicuous consumption in consumers, or to use branded messages to ...
Browning, Christopher S.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Cultural value perception in the memorable tourism experience [PDF]

open access: yes, 2013
Tourism management curriculum, if its ultimate objective is to give an introduction to the modern trends in tourism management and marketing and to prepare future destination managers, must inevitably incorporate – together with all their theoretical and
Horvath, Zsuzsanna
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Mitos e imaginarios migratorios en la recepción de la televisión en Marruecos [PDF]

open access: yes, 2013
The analysis of the discourses of Moroccan candidates to migrate regarding the images offered by Western television shows a mythical imaginary of life opportunities in the North.
Benítez Eyzaguirre, Lucía Isabel
core   +2 more sources

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