Results 71 to 80 of about 81,344 (281)

Explorative Nanophilosophy as Tecnoscienza: An Italian Perspective on the Role of Speculation in Nanoindustry [PDF]

open access: yes, 2019
There are two primary camps in which nanotechnology today can be categorized normal nanotechnology and speculative nanotechnology. The birth of nanotechnology proper was conceived through discourses of speculative nanotechnology.
Umbrello, Steven
core   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Fields in Motion, Fields of Friction: Tales of Betrayal and Promise from Kangra District, India [PDF]

open access: yes, 2014
Over a period of five decades, Kangra District, located in the mountainous northern Indian state of Himachal Pradesh, has been continually si(gh)ted within different development imaginaries that have evolved at particular configurations of scale and time
Johari, Radhika
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The challenges of "upstream" communication and public engagement for Irish nanotechnology [PDF]

open access: yes, 2009
This paper sets out some challenges for Ireland’s contribution to nanotechnology public engagement in the context of current STS and science communication theoretical practice approaches.
Murphy, Padraig
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

La ricchezza del bio: pratiche e immaginari in una rete di eccellenza vitivinicola nel Chianti classico (Toscana)

open access: yesIm@go. A Journal of the Social Imaginary, 2016
The essay explores organic practices and imaginaries in a wine terroir in the Chianti Classico, in Tuscany. The ethnography sheds light on how organic styles of production activates agro-ecological innovations and forms of socialization of nature ...
Michela Badii
doaj  

Linear groups in Galois fields. A case study of tacit circulation of explicit knowledge [PDF]

open access: yes, 2012
This preprint is the extended version of a paper that will be published in the proceedings of the Oberwolfach conference "Explicit vs tacit knowledge in mathematics" (January 2012). It presents a case study on some algebraic researches at the turn of the
Brechenmacher, Frederic
core   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

"It's all about sharing": Can circular initiatives be autonomous food spaces?

open access: yesJournal of Political Ecology
In this article I place into dialogue the challenges of the circular economy (CE) with political ecology by using the notion of autonomy. I examine two circular food initiatives in the capital city region of Brussels, Belgium, a cooperative supermarket ...
deborah lambert
doaj   +2 more sources

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