The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge +14 more
wiley +1 more source
Fractional dynamics and optical soliton propagation in mono-mode fibers via the Fokas system. [PDF]
Iqbal N +5 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Directional Coupling of Surface Plasmon Polaritons at Exceptional Points in the Visible Spectrum. [PDF]
Abdulghani A +5 more
europepmc +1 more source
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang +8 more
wiley +1 more source
Surface Charge-Induced Scattering Enhancement of Diverse Dielectric Nanoscale Particles: A Simulation Study. [PDF]
Zhang S +5 more
europepmc +1 more source
Gallium-doped zinc oxide semiconductor nanoparticles for plasmonic applications: a combined experimental and computational study. [PDF]
Rao Nulakani NV +4 more
europepmc +1 more source
Hydrogen storage potential of cubic InXH<sub>3</sub> (X = Be, Mg, Ca, Sr, Ba, Ra) hydride perovskites: a comprehensive first principles investigation. [PDF]
Amin AB +4 more
europepmc +1 more source
Phase-Resolved Two-Dimensional Infrared Spectroscopy of Solution-Phase Vibrational Polaritons on Gold Antenna Meta-Surfaces. [PDF]
Sufrin S, Cohn B, Chuntonov L.
europepmc +1 more source

