Results 81 to 90 of about 5,758,297 (346)

Descartes on the Infinity of Space vs. Time [PDF]

open access: yes, 2018
In two rarely discussed passages – from unpublished notes on the Principles of Philosophy and a 1647 letter to Chanut – Descartes argues that the question of the infinite extension of space is importantly different from the infinity of time.
Gorham, Geoffrey
core  

Time in the ontology of Cornelius Castoriadis [PDF]

open access: yes, 2017
We can locate the problematic of time within three philosophical questions, which respectively designate three central areas of philosophical reflection and contemplation. These are: 1) The ontological question, i.e.
Schismenos, Alexandros
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

FOREWORD. THE IMAGINARY OF THE LINGUISTIC IMAGINARY

open access: yesStudia Universitatis Babeş-Bolyai. Philologia, 2023
The concept of linguistic imaginary is still in the process of being accepted and taken seriously in the Romanian academic world. Although it was coined a few decades ago by Anne-Marie Houdebine-Gravaud (2002), many Romanian linguists regard it with ...
Elena PLATON, Ioana-Silvia SONEA
doaj   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Imaginary Political Reality: Constructing the National Image

open access: yesВестник Кемеровского государственного университета. Серия: политические, социологические и экономические науки
The ontology of contemporary political reality is subjective, because it is an artificial national world that provides a vivid semantic reality in order to resist the deconstruction of political semantics.
Nina G. Shcherbinina, Elena G. Avanesova
doaj   +1 more source

Holographic Meson Melting

open access: yes, 2007
The plasma phase at high temperatures of a strongly coupled gauge theory can be holographically modelled by an AdS black hole. Matter in the fundamental representation and in the quenched approximation is introduced through embedding D7-branes in the AdS-
A. Karch   +35 more
core   +4 more sources

Extinct, obscure or imaginary: The lizard species with the smallest ranges

open access: yesDiversity and Distributions: A journal of biological invasions and biodiversity, 2017
Small geographic ranges make species especially prone to extinction from anthropogenic disturbances or natural stochastic events. We assemble and analyse a comprehensive dataset of all the world's lizard species and identify the species with the smallest
Shai Meiri   +28 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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