Results 21 to 30 of about 2,856,123 (268)
4th Internatinal TPCF Preclinical Imaging Symposium
Frontiers in Biomedical Technologies, 2021 Due to the huge costs and time spent for development of new drugs (around almost $ 1 billion (USD) and 12 Years), investing on the preclinical phase of drug development could be regarded as a great investment for de-risking the clinical phases ...
4th Internatinal TPCF Preclinical Imaging
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5th Internatinal TPCF Preclinical Imaging Symposium
Frontiers in Biomedical Technologies, 2023 Preclinical imaging is the visualization of living animals for research purposes, such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in ...
5th Internatinal TPCF Preclinical Imaging
doaj
Nanobodies: Next Generation of Cancer Diagnostics and Therapeutics
Frontiers in Oncology, 2020 The development of targeted medicine has greatly expanded treatment options and spurred new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging as a prevalent treatment in recent years.
Emily Y. Yang +4 more
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Frontiers in Cellular Neuroscience, 2020 For sensory systems of the brain, the dynamics of an animal’s own sampling behavior has a direct consequence on ensuing computations. This is particularly the case for mammalian olfaction, where a rhythmic flow of air over the nasal epithelium entrains ...
Tobias Ackels +6 more
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A novel framework for image-to-image translation and image compression
Neurocomputing, 2022 Data-driven paradigms using machine learning are becoming ubiquitous in image processing and communications. In particular, image-to-image (I2I) translation is a generic and widely used approach to image processing problems, such as image synthesis, style transfer, and image restoration.
Fei Yang 0004 +4 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Medical applications at CERN and the ENLIGHT Network
Frontiers in Oncology, 2016 State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centres: from imaging technologies, to dedicated accelerators for cancer therapy and nuclear ...
Manjit eDosanjh +3 more
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Frontiers in Cardiovascular Medicine, 2022 Induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) represent an attractive resource for cardiac regeneration. However, survival and functional integration of transplanted iPS-CM is poor and remains a major challenge for the development of ...
Klaus Neef +7 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source