Results 81 to 90 of about 14,342,235 (381)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Putting a Finishing Touch on GECIs
Frontiers in Molecular Neuroscience, 2014 More than a decade ago genetically encoded calcium indicators (GECIs) entered the stage as new promising tools to image calcium dynamics and neuronal activity in living tissues and designated cell types in vivo.
Tobias eRose +3 more
doaj +1 more source
Radiomics in medical imaging—“how-to” guide and critical reflection
Insights into Imaging, 2020 Radiomics is a quantitative approach to medical imaging, which aims at enhancing the existing data available to clinicians by means of advanced mathematical analysis.
J. V. van Timmeren +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
3rd TPCF Preclinical Symposium Imaging(TPIS 2020)
Frontiers in Biomedical Technologies, 2020 The path of discovering/designing a molecule to developing a novel drug could take up to an average of 12 years and costs around $1 billion (USD). Preclinical phase is a major step on this path and is the part where scientists perform additional studies ...
3rd TPCF Preclinical Symposium Imaging (TPIS 2020)
doaj
Frontiers in Aging Neuroscience, 2018 In addition to extracellular β-amyloid plaques and intracellular neurofibrillary tangles, neuroinflammation has been identified as a key pathological characteristic of Alzheimer’s disease (AD).
Zhiwei Shen, Xinjie Bao, Renzhi Wang
doaj +1 more source
Recent Advances of Hyperspectral Imaging Technology and Applications in Agriculture
Remote Sensing, 2020 Remote sensing is a useful tool for monitoring spatio-temporal variations of crop morphological and physiological status and supporting practices in precision farming.
B. Lu +4 more
semanticscholar +1 more source
Signal-to-noise properties of correlation plenoptic imaging with chaotic light
, 2019 Correlation Plenoptic Imaging (CPI) is a novel imaging technique, that exploits the correlations between the intensity fluctuations of light to perform the typical tasks of plenoptic imaging (namely, refocusing out-of-focus parts of the scene, extending ...
D'Angelo, Milena +4 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Frontiers in Neurology, 2017 BackgroundFew studies have investigated structural imaging findings of cerebral venous thrombosis (CVT) in China. The structural imaging [head computed tomography (CT) and routine brain magnetic resonance imaging (MRI)] can assess any parenchymal lesion ...
Li-xin Zhou +7 more
doaj +1 more source