Results 91 to 100 of about 4,405,442 (293)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Sector Imaging Radar for Enhanced Vision [PDF]

open access: yes, 2001
SIREV (Sector Imaging Radar for Enhanced Vision) is an innovative radar system which can supply high-quality images of a sector in front of an aircraft under almost every weather condition.
Witte, Franz   +5 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

View synthesis for depth from motion 3D x-ray imaging. [PDF]

open access: yes, 2009
The depth from motion or kinetic depth X-ray imaging (KDEX) technique is designed to enhance the luggage screening at airport checkpoints. The technique requires multiple views of the luggage to be obtained from an arrangement of linear X-ray detector ...
Liu, Y
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A practical acceleration algorithm for real-time imaging

open access: yes, 2009
A practical acceleration algorithm for real-time magnetic resonance imaging (MRI) is presented. Neither separate training scans nor embedded training samples are used. The Kalman filter based algorithm provides a fast and causal reconstruction of dynamic
Sumbul, Uygar   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Advances in Ptychography [PDF]

open access: yes, 2011
Ptychography aims to completely revolutionise imaging in visible light, X-rays and Electron wavelengths by providing a robust platform for sub-Nyquist high-resolution real-time imaging.
Edo, Tega Boro
core  

Noninvasive molecular imaging of neuroinflammation [PDF]

open access: yes, 2011
Inflammation is a highly dynamic and complex adaptive process to preserve and restore tissue homeostasis. Originally viewed as an immune-privileged organ, the central nervous system (CNS) is now recognized to have a constant interplay with the innate and
Jacobs, A.H. (Andreas)   +15 more
core   +1 more source

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