Results 51 to 60 of about 18,911,738 (262)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery

open access: yesNature Communications, 2021
The mitochondrion is an important sub-cellular organelle responsible for the cellular energetic source and processes. Owing to its unique sensitivity to heat and reactive oxygen species, the mitochondrion is an appropriate target for photothermal and ...
Lei Jiang   +6 more
doaj   +1 more source

Imaging performance of phase-contrast breast computed tomography with synchrotron radiation and a CdTe photon-counting detector.

open access: yesPhysica medica (Testo stampato), 2016
PURPOSE Within the SYRMA-CT collaboration based at the ELETTRA synchrotron radiation (SR) facility the authors investigated the imaging performance of the phase-contrast computed tomography (CT) system dedicated to monochromatic in vivo 3D imaging of the
A. Sarno   +8 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Zoom Auxiliary Imaging Lens Design for a Modulation Transfer Function Test System

open access: yesPhotonics
In this paper, we propose a zoom auxiliary imaging lens based on the four-component mechanical zoom method for a modulation transfer function (MTF) test system. The auxiliary imaging lenses of the current MTF test system typically use fixed-focus optical
Yicheng Sheng   +5 more
doaj   +1 more source

Polyrotaxane-based supramolecular theranostics

open access: yesNature Communications, 2018
The development of smart theranostic systems with favourable biocompatibility, high loading efficiency, excellent circulation stability, potent anti-tumour activity, and multimodal diagnostic functionalities is of importance for future clinical ...
Guocan Yu   +17 more
doaj   +1 more source

In situ forming oxygen/ROS-responsive niche-like hydrogel enabling gelation-triggered chemotherapy and inhibition of metastasis

open access: yesBioactive Materials, 2023
Though the development of the diverse hypoxia-activated prodrugs (HAPs) has made great progresses in the last several decades, current cancer therapy based on HAPs still suffers many obstacles, e.g., poor therapeutic outcome owing to hard deep reaching ...
Shi-Xiong Chen   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Impact of High-Voltage Generator Inverter Frequency on Imaging Performance of Digital Radiography System

open access: yesZhongguo yiliao qixie zazhi
This paper introduces and analyzes the principles and structure inside the high-voltage generator, and for the first time proposes the viewpoint that using an inverter to increase the inverter frequency can enhance the imaging performance of the digital ...
Tao LI, Xiaobin MA, Zheng FAN
doaj   +1 more source

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