Results 121 to 130 of about 6,983,337 (380)

Requirement analysis in medical phantom development: a survey tool approach with an illustrative example of a multimodal deformable pelvic phantom

open access: yesFrontiers in Physics
IntroductionMedical phantoms play a crucial role in medical imaging and therapy. However, the successful development of these phantoms heavily relies on a comprehensive understanding of the requirements specific to each application.MethodsIn this paper ...
Marie Wegner   +5 more
doaj   +1 more source

Design of a Breast Phantom for Quantitative Magnetic Resonance Imaging

open access: yesJournal of Magnetic Resonance Imaging, 2016
We present a breast phantom designed to enable quantitative assessment of measurements of T1 relaxation time, apparent diffusion coefficient (ADC), and other attributes of breast tissue, with long‐term support from a national metrology institute.
Kathryn E Keenan   +8 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Regularized Dual Averaging Image Reconstruction for Full-Wave Ultrasound Computed Tomography

open access: yes, 2017
Ultrasound computed tomography (USCT) holds great promise for breast cancer screening. Waveform inversion-based image reconstruction methods account for higher order diffraction effects and can produce high-resolution USCT images, but are computationally
Anastasio, Mark A.   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Balanced multi-shot EPI for accelerated Cartesian MRF: An alternative to spiral MRF

open access: yes, 2018
The main purpose of this study is to show that a highly accelerated Cartesian MRF scheme using a multi-shot EPI readout (i.e. multi-shot EPI-MRF) can produce good quality multi-parametric maps such as T1, T2 and proton density (PD) in a sufficiently ...
Benjamin, Arnold Julian Vinoj   +6 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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