Results 161 to 170 of about 6,210,221 (335)

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Accuracy of patient dose estimation in cone beam computed tomography in breast irradiation by size‐specific dose estimates with position correction

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract This study aims to investigate the effects of the position correction of size‐specific dose estimates (SSDE) on patient dose estimation in cone beam computed tomography (CBCT). The relationship between the phantom position and absorbed dose in the right breast was studied using optically stimulated luminescence dosimeters and a simulated human
Hiroyuki Ueno, Kosuke Matsubara, Sayuri Bou, Masato Hizume   +3 more
wiley   +1 more source

An international phantom study of inter-site variability in Technetium-99m image quantification: analyses from the TARGET radioembolization study

EJNMMI Physics
Background Personalised multi-compartment dosimetry based on [99mTc]Tc-MAA is a valuable tool for planning 90Y radioembolization treatments. The establishment and effective application of dose–effect relationships in yttrium-90 (90Y) radioembolization ...
Grace Keane, Rob van Rooij, Marnix Lam, S. Cheenu Kappadath, Bilal Kovan, Stephanie Leon, Matthew Dreher, Kirk Fowers, Hugo de Jong   +8 more
doaj   +1 more source

UWB device for breast microwave imaging: phantom and clinical validations

Measurement, 2019
Alessandro Vispa, Lorenzo Sani, Martina Paoli, Alessandra Bigotti, Giovanni Raspa, N. Ghavami, S. Caschera, M. Ghavami, Michele Duranti, G. Tiberi   +9 more
semanticscholar   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Evaluation of patient doses for routine digital radiography procedures toward establishing an institutional diagnostic reference levels: A case study in Sri Lanka

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract The present study was conducted as part of a comprehensive work to establish National Diagnostic Reference Levels (NDRLs) in Sri Lanka for the first time. DRLs can be used as an effective optimization tool for identifying unusually high or low patient doses during X‐ray examinations.
Sachith Welarathna, Sivakumar Velautham, Mihira Wanninayake, Sivananthan Sarasanandarajah   +3 more
wiley   +1 more source

Assessment of ultrasound image quality in a reference phantom using gel and liquid standoff pads

WFUMB Ultrasound Open
Background: and Methods: This paper presents a review of image quality in ultrasound imaging when using gel and liquid standoff pads, compared to imaging without a standoff pad. Imaging metrics assessed are lateral resolution, nearfield target intensity,
Catherine Paverd, Alexander Martin, Marga Rominger, Lisa Ruby   +3 more
doaj  

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

FUNDAMENTAL STUDY OF CEREBRAL BLOOD FLOW IMAGING WITH SINGLE-PHOTON-EMISSION COMPUTED TOMOGRAPHY. : COMPARISON AMONG PHANTOM IMAGES USING ^<123>I PRODUCED BY THE (p, 2n) OR (p, 5n) REACTION AND ^<99m>Tc NUCLIDE

, 1987
Shinichi Yanagimoto, T Tomomitsu, Hiroaki Mimura, Naomasa Narihiro, Koushi Ishii, Hiroo Hiji   +5 more
openalex   +2 more sources

Three-Dimensional Image Registration of Phantom Vertebrae for Image-Guided Surgery: A Preliminary Study [PDF]

, 2002
Diane M. Muratore, Jeannette Herring Russ, Benoît M. Dawant, Robert L. Galloway   +3 more
openalex   +1 more source