Results 81 to 90 of about 6,210,221 (335)

Comprehensive phantom for interventional fluorescence molecular imaging

Journal of Biomedical Optics, 2016
. Fluorescence imaging has been considered for over a half-century as a modality that could assist surgical guidance and visualization. The administration of fluorescent molecules with sensitivity to disease biomarkers and their imaging using a ...
M. Anastasopoulou, M. Koch, D. Gorpas, A. Karlas, U. Klemm, P. Garcia-Allende, V. Ntziachristos   +6 more
semanticscholar   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Characterisation of a phantom for multiwavelength quantitative photoacoustic imaging

Physics in Medicine and Biology, 2016
Quantitative photoacoustic imaging (qPAI) has the potential to provide high- resolution in vivo images of chromophore concentration, which may be indicative of tissue function and pathology.
Martina Fonseca, B. Zeqiri, P. Beard, B. Cox   +3 more
semanticscholar   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Stereoscopic Near-Infrared Fluorescence Imaging: A Proof of Concept Toward Real-Time Depth Perception in Surgical Robotics

Frontiers in Robotics and AI, 2019
The increasing use of surgical robotics has provoked the necessity for new medical imaging methods. Many assistive surgical robotic systems influence the surgeon's movements based on a model of constraints and boundaries driven by anatomy.
Maxwell J. Munford, Ferdinando Rodriguez y Baena, Stuart Bowyer   +2 more
doaj   +1 more source

Phantom-based characterization of distortion on a magnetic resonance imaging simulator for radiation oncology

Physics in Medicine and Biology, 2016
One of the major issues potentially limiting treatment planning with solely MR images is the possibility of geometric distortion inherent in MR images.
Ke Huang, Yue Cao, Umar Baharom, J. Balter   +3 more
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Quantitative PET/CT Scanner Performance Characterization Based Upon the Society of Nuclear Medicine and Molecular Imaging Clinical Trials Network Oncology Clinical Simulator Phantom

Journal of Nuclear Medicine, 2015
The Clinical Trials Network (CTN) of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) operates a PET/CT phantom imaging program using the CTN’s oncology clinical simulator phantom, designed to validate scanners at sites that wish to ...
J. Sunderland, P. Christian
semanticscholar   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Requirement analysis in medical phantom development: a survey tool approach with an illustrative example of a multimodal deformable pelvic phantom

Frontiers in Physics
IntroductionMedical phantoms play a crucial role in medical imaging and therapy. However, the successful development of these phantoms heavily relies on a comprehensive understanding of the requirements specific to each application.MethodsIn this paper ...
Marie Wegner, Marie Wegner, Jonte Schmiech, Eve Sobirey, Dieter Krause, Elisabetta Gargioni   +5 more
doaj   +1 more source