Results 221 to 230 of about 87,925 (315)

A 37‐Year Retrospective Analysis Reveals a High Rate of Cutaneous Angiosarcoma of the Scalp in Okinawa, Japan

Cancer Science, Volume 116, Issue 4, Page 1059-1067, April 2025.
A 37‐year retrospective analysis has revealed an exceptionally high rate of angiosarcoma of the scalp in Okinawa, Japan. This study represents the first identification of Okinawa as a hotspot for this rare cancer, the epidemiology of which has been insufficiently studied.
Aoi Ohira, Daisuke Utsumi, Ryoko Awazawa, Nobutake Yagi, Tsuyoshi Awazawa, Sayaka Yamaguchi, Teruki Yanagi, Kenzo Takahashi   +7 more
wiley   +1 more source

Clonal eosinophilia with exclusive pulmonary involvement driven by PDGFRA rearrangement treated with imatinib: A case report. [PDF]

Leuk Res Rep
Mlayah Z, Ben-Rekaya I, Bizid I, Slama N, Boukhris S, Laatiri MA.   +5 more
europepmc   +1 more source

CML With Mutant ASXL1 Showed Decreased Sensitivity to TKI Treatment via Upregulation of the ALOX5‐BLTR Signaling Pathway

Cancer Science, Volume 116, Issue 4, Page 1115-1125, April 2025.
We generated cell lines with inducible expression of ASXL1 mutations and found that ASXL1 mutation‐induced cell lines exhibited reduced ABL1 TKI sensitivity. We identified ALOX5 as one of the top upregulated genes under the expression of mutated ASXL1 and high expression of ALOX5 conferring TKI resistance. Inhibition of the ALOX5‐BLTR signaling pathway
Naoki Miyashita, Masahiro Onozawa, Kohei Kasahara, Toshihiro Matsukawa, Yasuhito Onodera, Kohjin Suzuki, Tomoiku Takaku, Takanori Teshima, Takeshi Kondo   +8 more
wiley   +1 more source

Chronic Eosinophilic Leukemia Positive for FIP1L1-PDGFRa. [PDF]

Cureus
Haydon SJ, Ross DE, Caucci S, Clark S, Hrinczenko B.   +4 more
europepmc   +1 more source

Current results on the use of imatinib mesylate in patients with relapsed philadelphia chromosome positive leukemia after allogeneic or syngeneic hematopoietic stem cell transplantation

, 2003
Andrew J. Ullmann, Georg Heß, Karin Kolbe, Anne Friedrich-Freksa, Ralf G. Meyer, Harald Gschaidmeier, Christoph Huber, Thomas Fischer   +7 more
openalex   +2 more sources

The Adverse Impact of Tyrosine Kinase Inhibitors on Wound Healing and Repair

International Wound Journal, Volume 22, Issue 4, April 2025.
ABSTRACT Tyrosine kinase inhibitors (TKIs) can treat various cancers, primarily through their antiangiogenic effects. However, as angiogenesis is crucial for successful wound healing, TKIs may adversely impact wound repair. This review analysed all 63 FDA‐approved TKIs and identified evidence for wound healing and repair implications in 24 agents.
William J. Nahm, Vincent Falanga
wiley   +1 more source

Imatinib on target in stroke recovery. [PDF]

J Clin Invest
Kwon HR, Olson LE.
europepmc   +1 more source

Chromosomal abnormalities in Ph- cells of patients on imatinib [PDF]

, 2003
Mary Frances McMullin, Mervyn Humphreys, Jenny Byrne, Nigel H. Russell, R Cuthbert, Michael O’Dwyer   +5 more
openalex   +1 more source

Gastrointestinal stromal tumor in patient with neurofibromatosis type 1: A case report. [PDF]

Int J Surg Case Rep
Ibrahimi A, Lachkar S, Boualaoui I, El Sayegh H, Nouini Y.   +4 more
europepmc   +1 more source

Treatment of rheumatoid arthritis with imatinib mesylate: clinical improvement in three refractory cases [PDF]

, 2003
Kari K. Eklund, Heikki Joensuu
openalex   +1 more source