Results 71 to 80 of about 224,004 (328)

CLASSIFICATION BOOSTING IN IMBALANCED DATA

open access: yesMalaysian Journal of Science, 2019
Most existing classification approaches assumed underlying training data set to be evenly distributed. However, in the imbalanced classification, the training data set of one majority class could far surpass those of the minority class. This becomes a problem because it’s usually produces biased classifiers that have a higher predictive accuracy over ...
Sinta Septi Pangastuti   +3 more
openaire   +2 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

A Classification Method Based on Feature Selection for Imbalanced Data

open access: yesIEEE Access, 2019
Imbalanced data are very common in the real world, and it may deteriorate the performance of the conventional classification algorithms. In order to resolve the imbalanced classification problems, we propose an ensemble classification method that ...
Yi Liu   +4 more
doaj   +1 more source

Integrative machine learning approach for multi-class SCOP protein fold classification [PDF]

open access: yes, 2003
Classification and prediction of protein structure has been a central research theme in structural bioinformatics. Due to the imbalanced distribution of proteins over multi SCOP classification, most discriminative machine learning suffers the well-known ‘
Deville, Y, Gilbert, D, Tan, A C
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

DPC-SMOTE Over-sampling Algorithm for Imbalanced Data Classification

open access: yesJournal of Harbin University of Science and Technology
An oversampling algorithm based on density peak clustering is proposed to solve the problem of noise and imbalance among classes in imbalanced data sets.
LIU Zhihan, ZHANG Zhonglin, ZHAO Lei
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Partial Resampling of Imbalanced Data

open access: yes, 2022
Imbalanced data is a frequently encountered problem in machine learning. Despite a vast amount of literature on sampling techniques for imbalanced data, there is a limited number of studies that address the issue of the optimal sampling ratio. In this paper, we attempt to fill the gap in the literature by conducting a large scale study of the effects ...
Kamalov, Firuz   +2 more
openaire   +2 more sources

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan   +12 more
wiley   +1 more source

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