Results 121 to 130 of about 141,868 (281)

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

CCNETS: A Modular Causal Learning Framework for Pattern Recognition in Imbalanced Datasets

Applied Sciences
Handling class imbalance remains a central challenge in machine learning, particularly in pattern recognition tasks where identifying rare but critical anomalies is of paramount importance. Traditional generative models often decouple data synthesis from
Hanbeot Park, Yunjeong Cho, Hunhee Kim
doaj   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Directional Perception in Game-Based Dyslexia Risk Screening: A Mouse-Tracking Analysis

Computers
Dyslexia is not easily observed from outward appearance alone; differences typically emerge through learning performance and certain behavioral indicators.
Natsinee Tangsiripaiboon, Sakgasit Ramingwong, Kenneth Cosh, Narissara Eiamkanitchat, Lachana Ramingwong   +4 more
doaj   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

ActivityRDI: A Centralized Solution Framework for Activity Retrieval and Detection Intelligence Based on Knowledge Graphs, Large Language Models, and Imbalanced Learning

Machine Learning and Knowledge Extraction
We propose a centralized Activity Retrieval and Detection Intelligence (ActivityRDI) solution framework, demonstrate its application performance in network threat detection in detail, and show its generalization to other domains. Network threat detection
Lili Zhang, Quanyan Zhu
doaj   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

IA-KNNR: A Novel Imbalance-Aware Approach for Handling Multi-Label Class Imbalance Problem

IEEE Access
Multi-label learning (MLL) is a supervised learning where the classifier needs to learn from the data where one instance can belong to more than one class (label).
Himanshu Suyal, Shiv Naresh Shivhare, Gulshan Shrivastava, Rohit Singh, Ansh Singhal   +4 more
doaj   +1 more source

Generative AI‐Driven Accelerated Discovery of Passivation Molecules for Perovskite Solar Cells

Advanced Science, EarlyView.
A generative artificial intelligence (AI) framework combining a discriminative machine learning model (SMILES‐X) and a generative language model (GPT‐2) autonomously discovers new molecular passivators for perovskite solar cells (PSCs). Through an iterative design loop, over 100 000 candidates are generated and screened, and randomly selected molecules
Adroit T. N. Fajar, Guillaume Lambard, Jessie Manopo, Ruili Guo, Kevin Septioga, Rizfi F. Pari, Toshinori Matsushima, Zhanglin Guo   +7 more
wiley   +1 more source

Explainable AI With Imbalanced Learning Strategies for Blockchain Transaction Fraud Detection

Engineering Reports
Blockchain networks now support billions of dollars in daily transactions, making reliable and transparent fraud detection essential for maintaining user trust and financial stability.
Ahmed Abbas Jasim Al‐Hchaimi, M. A. Khalifa, Walid El‐Shafai   +2 more
doaj   +1 more source