Results 181 to 190 of about 4,807 (195)

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia   +8 more
wiley   +1 more source

Proprioceptive-augmented virtual reality influences the kinematic properties of movement imitation. [PDF]

open access: yesJ Neuroeng Rehabil
Bisio A   +6 more
europepmc   +1 more source

A Thickness‐Invariant Origami Robot With Integrated Actuation and Multimodal Locomotion

open access: yesAdvanced Science, EarlyView.
A thickness‐invariant variation on the Yoshimura origami pattern is used as the basis of a robot, allowing power, actuation, and control systems to be embedded within the thickened panels of the pattern. The robot uses multiple kinematic branches to achieve distinct modes of locomotion, such as walking, running, galloping, and turning. ABSTRACT Origami
Davis Wing   +4 more
wiley   +1 more source

Correlated Polymer‐Proton Hopping Enables Water‐Independent Fast Proton Transport in Poly(Ionic Liquid) Membranes

open access: yesAdvanced Science, EarlyView.
A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith   +11 more
wiley   +1 more source

A Physical Adaptive Material Motor Unit Neural Network: A Hygromorph Composite Material Machine

open access: yesAdvanced Science, EarlyView.
This study introduces a new class of material‐based intelligent machines. It presents a Physical Adaptive Material Motor Unit Neural Network, an assembly of smart 4D printed actuators and a controlling system that adapt through environmental interaction its shading behavior.
Charles de Kergariou   +2 more
wiley   +1 more source

Infants exposed to maternal type 1 diabetes: intrauterine epigenetic modifications and neurological development. [PDF]

open access: yesFront Endocrinol (Lausanne)
González-González NL   +13 more
europepmc   +1 more source

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

open access: yesAdvanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko   +8 more
wiley   +1 more source

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