Results 51 to 60 of about 177,603 (326)

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

IMM Filtering Algorithms for a Highly Maneuvering Fighter Aircraft: An Overview

Algorithms
The trajectory estimation of a highly maneuvering target is a challenging problem and has practical applications. The interacting multiple model (IMM) filter is a well-established filtering algorithm for the trajectory estimation of maneuvering targets ...
M. N. Radhika, Mahendra Mallick, Xiaoqing Tian   +2 more
doaj   +1 more source

Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking

Advanced Science, EarlyView.
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo‐crosslinking approach is presented that prolongs the lifetime of different structures in coacervate‐based artificial cells while maintaining dynamic formation.
Madelief A. M. Verwiel, Alexander B. Cook, Yiǧitcan Sümbelli, Nadia A. Erkamp, Jan C. M. van Hest   +4 more
wiley   +1 more source

Echocardiography interpretation training and internal medicine milestones: A pilot study

Journal of the Formosan Medical Association
Background/Purpose: The competency-based Internal Medicine Milestones (IMM) assesses physician training outcomes through six key competencies. This pilot study introduced IMM concepts through an echocardiography report interpretation course for ...
Li-Tan Yang, Meng-Han Tsai, Wang-Huei Sheng, Jiun-Yu Yu, Yi-Lwun Ho   +4 more
doaj   +1 more source

A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

Skeletal Muscle, 2018
Background The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofibers. The purpose of this study was
Carrie J. Finno, Giuliana Gianino, Sudeep Perumbakkam, Zoë J. Williams, Matthew H. Bordbari, Keri L. Gardner, Erin Burns, Sichong Peng, Sian A. Durward-Akhurst, Stephanie J. Valberg   +9 more
doaj   +1 more source

Improving Treatment of Noise Specification of Kalman Filtering for State Updating of Hydrological Models: Combining the Strengths of the Interacting Multiple Model Method and Cubature Kalman Filter

Water Resources Research, 2023
Filtering methods have been widely used to improve the forecast performances of hydrological models. Although extensive research has been carried out on filtering methods in the hydrology literature, researchers have not treated the noise statistics of ...
Y. Sun, X. Tian, W. Bao, S. Qu, Q. Li, Y. Chen, Z. Zhou, P. Shi   +7 more
doaj   +1 more source

Protection Against Cardiac Injury by Small Ca\u3csup\u3e2 +\u3c/sup\u3e-Sensitive K\u3csup\u3e+\u3c/sup\u3e Channels Identified in Guinea Pig Cardiac Inner Mitochondrial Membrane [PDF]

, 2013
We tested if small conductance, Ca2 +‐sensitive K+ channels (SKCa) precondition hearts against ischemia reperfusion (IR) injury by improving mitochondrial (m) bioenergetics, if O2‐derived free radicals are required to initiate protection via SKCa ...
Aldakkak, Mohammed, Camara, Amadou K.S., Cheng, Qunli, Gadicherla, Ashish K., Heisner, James S., Jiang, Ming Tao, Kwok, Wai-Meng, Stowe, David F., Yang, MeiYing, Zhou, Yifan   +9 more
core   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Mass transport of driven inelastic Maxwell mixtures

, 2018
Mass transport of a driven granular binary mixture is analyzed from the inelastic Boltzmann kinetic equation for inelastic Maxwell models (IMM).
Garzó, Vicente, Khalil, Nagi
core   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source