ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
The Role of Astrocyte-Neuron Interactions in Shaping Neuronal Maturation during Human Brain Development. [PDF]
Zhao M, Zhu Y.
europepmc +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Immature olfactory sensory neurons are intrinsically excitable and show maturation-dependent changes in voltage-gated Na<sup>+</sup> and K<sup>+</sup> currents. [PDF]
Ricci C +6 more
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Immunoinflammatory cells and Beta-defensin-3 in radicular cysts of primary and permanent teeth. [PDF]
Bertasso AS +8 more
europepmc +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Diagnostic Accuracy of Immature Platelet Fraction, Immature Reticulocyte Fraction, and Immature Granulocyte Percentage for Bacterial Sepsis: A Cross-Sectional Study. [PDF]
Choudhary A +5 more
europepmc +1 more source
Attention immaturity in late adolescence: Conflict adaptation with value associated stimuli
Daniel Dodgson, Jane E. Raymond
openalex +1 more source

