Results 61 to 70 of about 143,947 (215)
TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin +9 more
wiley +1 more source
Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed +5 more
wiley +1 more source
ABSTRACT Gastric teratoma is an extremely rare neoplasm in childhood. A 2-month-old male infant presented with progressive abdominal distension since birth. Clinical examination revealed a large palpable mass and was proceeded with ultrasonography followed by computed tomography (CT) for further evaluation.
Glory, Katiyar +2 more
openaire +2 more sources
NMDAR‐antibody encephalitis: Seizure semiology and EEG findings
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus +6 more
wiley +1 more source
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha +6 more
wiley +1 more source
Abstract Objective Endometriosis is a chronic inflammatory disease, with inflammation relating to pathogenesis and staging. We compared inflammatory indices and clinical characteristics between patients with ovarian endometriomas and those with benign ovarian tumors to evaluate their diagnostic value and identify affordable blood markers for diagnosis ...
Pingping Su +5 more
wiley +1 more source
Immature Ovarian Teratoma with Gliomatosis Peritonei- an unusual finding
Immature ovarian teratoma is a rarely seen germ cell tumor and Gliomatosis peritonei (GP) is a rare condition that occurs almost exclusively in the setting of ovarian immature teratoma.
Jinnatun Nur +2 more
core +1 more source
Teratoma is a germ cell neoplasm of the ovary. There are two main types of teratomas: mature teratoma and immature teratoma. Teratomas can rarely be associated with disseminated deposits. It is most commonly seen in immature teratomas.
Rajashree Jeyaraman +3 more
doaj +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
Congenital immature teratoma of the tongue: An autopsy case
Congenital immature teratoma of the tongue is a very rare form of extragonadal teratoma. We report an infant autopsy case of a huge congenital immature teratoma protruding from the tongue of a female infant born to a woman at 28 weeks' gestation of her ...
김진, 박찬일
core +1 more source

