Results 31 to 40 of about 124,166 (311)

GASTROESOPHAGEAL REFLUX IN NEWBORNS AND INFANTS (II) [PDF]

open access: yesRomanian Journal of Pediatrics, 2016
Gastroesophageal reflux in newborns and infants is particularized by pathogeny, diagnosis and therapeutical approach, functional immaturity of the digestive tract, the anatomic immaturity of the Hiss lower esophageal sphincter and lower gastric acidity.
Valeriu V. Lupu   +3 more
doaj   +1 more source

Karl Popper's Philosophical Breakthrough [PDF]

open access: yes, 2004
Despite his well-known deductivism, in his early (unpublished) writings, Popper held an inductivist position. Up to 1929 epistemology entered Popper's reflections only as far as the problem was that of the justification of the scientific character of ...
Gattei, Stefano
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Gene Expression Signatures of Immaturity, Decreased pH, and Neural Hyperexcitation in the Hippocampus of Alzheimer's Disease Model Mice

open access: yesNeuropsychopharmacology Reports
Aims Alzheimer's disease (AD) is a leading cause of dementia, with increasing prevalence. Mutations in genes like MAPT, PSEN1, and PSEN2 are risk factors, leading to the development of several AD model mice.
Sayaka Naganishi   +2 more
doaj   +1 more source

Post-weaning folate deficiency induces a depression-like state via neuronal immaturity of the dentate gyrus in mice

open access: yesJournal of Pharmacological Sciences, 2020
Folate deficiency has been suggested as a risk factor for depression in preclinical and clinical studies. Several hypotheses of mechanisms underlying folate deficiency-induced depressive symptoms have been proposed, but the detailed mechanisms are still ...
Shoji Nishida   +7 more
doaj   +1 more source

Arias icterus: Prolonged unconjugated hyperbilirubinemia caused by breast milk [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2007
Introduction Breast milk jaundice occurs in 1-2% of healthy breast-fed newborns and young infants. It develops as the result of liver immaturity and the inhibitory effect of mother’s milk to the clearance of unconjugated bilirubin.
Mladenović Marija   +9 more
doaj   +1 more source

Relative Age Effect in Attention Deficit/Hyperactivity Disorder at Various Stages of the Medicalization Process

open access: yesChildren, 2022
Diagnosis and pharmacological treatment of ADHD are more common among the youngest children in a classroom, born in the months immediately preceding the school entry cutoff date. The mechanisms behind this phenomenon, called the relative age effect (RAE),
Marie-Christine Brault   +3 more
doaj   +1 more source

Some Considerations about Pain in the Child that was Born Premature [PDF]

open access: yes, 2017
Every single child born before completing the 37 weeks of gestational age (GA) is considered by major organizations such as UNICEF [1] and OMS [2] as premature.
Gómez, María Celeste
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Retinal immaturity at first screening and retinopathy of prematurity: Image-based validation of 1202 eyes of premature infants to predict disease progression

open access: yesIndian Journal of Ophthalmology, 2019
Purpose: To use the extent of retinal immaturity at the first visit to predict progression to any stage and treatment-requiring retinopathy of prematurity (ROP).
Chaitra Jayadev   +8 more
doaj   +1 more source

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