Results 121 to 130 of about 661,741 (245)
Contact Allergens Relevant to LGBTQI Populations: A Narrative Review and Practical Considerations
Australasian Journal of Dermatology, EarlyView.ABSTRACT Allergic contact dermatitis (ACD) is a common inflammatory skin disorder with significant morbidity across populations. Sexual and gender minority (SGM) individuals, including LGBTQI populations, are exposed to unique allergens due to gender‐affirming medical therapies, surgical interventions, cosmetics and grooming practices, sexual health ...
Nicholas van Rooij
wiley +1 more source
Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination
Allergy, EarlyView.We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera +14 more
wiley +1 more source
Frontiers in PharmacologyBackgroundRituximab, an anti-CD20 monoclonal antibody, is an established treatment for primary membranous nephropathy (PMN). While generally well-tolerated, its recognized adverse effects include infusion-related reactions and immediate hypersensitivity.
Weidong Huang +5 more
doaj +1 more source
A Modified Basophil Activation Test for the Clinical Management of Immediate Hypersensitivity Reactions to Paclitaxel: A Proof-of-Concept Study. [PDF]
Cancers (Basel), 2023 La Sorda M +16 more
europepmc +1 more source
Allergy, EarlyView.ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
Contrast media hypersensitivity - scope of the problem.
, 2005 Hypersensitivity reactions to contrast media (CM) are frequent causes of anaphylactically induced fatalities. Adverse events after CM exposure are classified into immediate and non-immediate reactions, with differing pathomechanisms.
Brockow, K, Brockow, K.
core +1 more source
Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source