Results 221 to 230 of about 94,038 (306)

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

Early‐life Giardia infection and behavioural dysregulation in two dogs: A case‐based exploration of the gut microbiome–brain axis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This case report describes two dogs exhibiting severe behavioural problems, both diagnosed with early‐life giardiasis and raised in environments lacking adequate maternal care and socialisation. Both dogs experienced chronic gastrointestinal and dermatological issues, as well as prolonged early‐life stress, which likely contributed to ...
Daniëlle Hartman   +3 more
wiley   +1 more source

Double‐Blind Placebo Challenge Confirmation of Diphenhydramine Allergy

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Diphenhydramine, a first‐generation H1–antihistamine commonly used for allergic symptom relief and infusion premedication, rarely causes true systemic hypersensitivity. When suspected reactions are mild and subjective—particularly in anxious patients—objective confirmation is essential.
Ruchi Patel   +2 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Incidence and Risk Factors of Immediate Hypersensitivity Reactions and Immunisation Stress-related Responses with COVID-19 mRNA Vaccine

open access: yes, 2022
Imai K   +18 more
europepmc   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan   +3 more
wiley   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1047-1056, April 2026.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout   +6 more
wiley   +1 more source

Endoscopic resection of polypoid solitary rectal ulcer: A novel first‐line therapeutic strategy using snare‐assisted mucosal and fibrosis resection

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives To propose a novel first‐line endoscopic therapy for treating polypoid lesions in solitary rectal ulcer syndrome (P‐SRUS), the rarest and most challenging subtype of SRUS, which encompasses various endoscopic findings including mucosal erythema, superficial or deep ulcers, and polypoid lesions.
Mojgan Forootan   +12 more
wiley   +1 more source

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