Results 241 to 250 of about 50,750 (264)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Fully Guided Implant Placement and Immediate Loading for the Restoration of the Edentulous Maxilla with a Fixed Dental Prosthesis: Report of Two Clinical Cases. [PDF]

Dent J (Basel)
Lampropoulos P, Sykaras N, Giannakopoulos NN, Kourtis S.   +3 more
europepmc   +1 more source

Comparative assessment of crestal bone level around non-hydrophilic and hydrophilic implants after immediate extraction: An <i>in vivo</i>study. [PDF]

Bioinformation
Seetha K, Gupta DK, Anant M, Jha A, Thakur A.   +4 more
europepmc   +1 more source

Immediate functional loading of implants in single tooth replacement: a prospective clinical multicenter study

Clinical Oral Implants Research, 2008
OBJECTIVES: The aim of the present study was to evaluate the outcome of immediate functional loading of implants in single-tooth replacement using two different installation procedures.
Mauro Donati, Tord Berglundh
exaly   +2 more sources

Immediate transmucosal implants using the principle of guided tissue regeneration. (II). A cross-sectional study comparing the clinical outcome 1 year after immediate to standard implant placement.

Clinical Oral Implants Research, 1996
The aim of the present study was to compare the peri-implant mucosal conditions 1 year after immediate transmucosal implant placement without or in combination with guided tissue regeneration with the situation after regular placement of transmucosal 1 ...
Urs Brägger, C H F Hammerle, Niklaus P Lang   +2 more
exaly   +2 more sources

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Immediate placement of single implants with or without immediate provisionalization in the maxillary aesthetic region: A 5‐year comparative study

Journal of Clinical Periodontology, 2021
, Diederik F M Hentenaar
exaly  

A prospective clinical study of bone augmentation techniques at immediate implants

Clinical Oral Implants Research, 2005
Stephen Chen, Ivan B Darby, Geoffrey G Adams   +2 more
exaly  

Clinical outcomes of immediate/early loading of dental implants. A literature review of recent controlled prospective clinical studies

Australian Dental Journal, 2008
Jan Gottlow
exaly