Results 171 to 180 of about 37,582 (305)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Exact implementation of boundary conditions for Immersed Boundary Methods

, 2015
Most CFD flow solvers obtain solution on boundary-conforming grids. Generating a boundary-conforming grid is, in general, a tedious and time consuming task.
Bansal, Karan
core  

Bridging the scales for deformable red blood cells simulation: from resolved immersed boundary to unresolved CFD-DEM. [PDF]

Biomech Model Mechanobiol
Porcaro C, Latt J, Saeedipour M.
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Composite B-spline regularized delta functions for the immersed boundary method: Divergence-free interpolation and gradient-preserving force spreading. [PDF]

J Comput Phys
Gruninger C, Griffith BE.
europepmc   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

On the stability of the finite element immersed boundary method

, 2006
The immersed boundary (IB) method is a mathematical formulation for fluid-structure interaction problems, where immersed incompressible visco-elastic bodies or boundaries interact with an incompressible fluid.
N. -pv, Luca Heltai, Tecnologie Informatiche, L. Heltai   +3 more
core   +1 more source

Numerical Simulation in Microvessels for the Design of Drug Carriers with the Immersed Boundary-Lattice Boltzmann Method. [PDF]

Micromachines (Basel)
Hou Y, Hu M, Sun D, Sun Y.
europepmc   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

FD/FEM Coupling with the Immersed Boundary Method for the Simulation of Aortic Heart Valves

, 2016
The ever-increasing available computational power allows for solving more complex physical problems spanning multiple physical domains. We present a numerical tool for simulating fluid-structure interaction between blood flow and the soft tissue of heart
Zolfaghari, Hadi, Krause, Rolf, Becsek, Barna Errol Mario, Nestola, Maria Giuseppina Chiara, Obrist, Dominik   +4 more
core