Results 31 to 40 of about 875,547 (246)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Lived Experience of Cultural Immersion [PDF]

, 2013
This article presents the findings of a grounded theory study of 3 graduate students\u27 lived experience of cultural immersion. Results indicated that participants experienced 3 phases (goal setting, interaction, and evaluation) and 4 themes (bias ...
Avrus, Elaine M., Bonham, Erica J., Cook, Jennifer, Hipolito-Delgado, Carlos P.   +3 more
core   +1 more source

Immersion microscopy based on photonic crystal materials

, 2005
Theoretical model of the enhanced optical resolution of the surface plasmon immersion microscope is developed, which is based on the optics of surface plasmon Bloch waves in the tightly bound approximation.
Davis, Christopher C., Elliott, Jill, Smolyaninov, Igor I., Wurtz, G., Zayats, Anatoly V.   +4 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]

, 1989
The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Anderson, Arendt, Arendt, Arendt, Atlas, Ballermann, Bourgorgnie, Campbell, Campbell, Chartier, Cody, Crozier, Cuneo, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Epstein, Gauer, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Goodfriend, Henriksen, Kramer, Laragh, Miki, Needleman, Nicholls, Ogihara, Pendergast, Pugh, Salerno, Sellars, Sherlock, Terblanche, Thibault, Wernze, Wernze, Wilkinson   +46 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Machine learning-based insights on the structural variations found in the C-terminal domains of differing human papillomavirus E6 and E7 protein models across geography, variants, and risk type

In Silico Research in Biomedicine
Human papillomavirus (HPV) are nonenveloped DNA viruses belonging to the Papillomaviridae family and, during HPV infection, the first viral genes expressed are the E6 and E7 oncogenes with the C-terminal domain mainly involved with oncogenicity.
Marni E. Cueno, Haruka Tamura, Felix Sugiyama, Kenichi Imai   +3 more
doaj   +1 more source

Total immersion crystal growth [PDF]

, 1987
Crystals of wide band gap materials are produced by positioning a holder receiving a seed crystal at the interface between a body of molten wide band gap material and an overlying layer of temperature-controlled, encapsulating liquid.
Morrison, Andrew D.
core   +1 more source