Results 111 to 120 of about 87,050 (289)

Highly Sensitive Detection of Human Serum Albumin Biomarker Using a Molecularly Imprinted Polymer‐Based Electrochemical Capacitance Sensor

open access: yesAdvanced Sensor Research, EarlyView.
An electrosynthesized protein‐imprinted polymer (poly(azo‐BBY)) enables probe‐free, real‐capacitance detection of human serum albumin at 0.02 ng mL−1 within a 0.25–3.0 ng mL−1 window. The device uses a redox‐mediator‐free architecture and maintains selectivity against common interferents, illustrating a simple, scalable route to high‐sensitivity ...
Heitor F. Trevizan   +4 more
wiley   +1 more source

Implementation of a SPOC on distance learning for improving the teaching-learning process

open access: yesTecnología, Ciencia y Educación, 2017
The introduction of the information and communication technologies (ICT) has been a major change in many aspects within the field of education, as in the form of information processing and acquire the knowledge on the part of the pupils, due to their ...
Raquel Aguayo Sarasa   +1 more
doaj  

Substrate‐Restricted Asymmetric Evolution of Solid‐State Nanopores

open access: yesAdvanced Theory and Simulations, EarlyView.
Standalone nanopores can either expand or shrink based on the nucleation mechanism. A substrate‐restricted asymmetric pore dynamics are uncovered ‐ top expansion and bottom shrinkage, with minimum aperture reduced and forming a conical geometry, driven by molecular migration along an energy potential gradient within nanopores.
Hongshuai Liu   +4 more
wiley   +1 more source

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker‐Based Drug Screening for Neurodegenerative Diseases

open access: yesAdvanced Science, EarlyView.
This work introduces an on‐chip, integrated plasmonic infrared microarray sensor that enables high‐throughput, label‐free drug screening targeting structural protein biomarkers in neurodegenerative diseases. Through ultra‐compact microwell arrays, the sensor achieves ultra‐sensitive, rapid, and multiplexed secondary structural analysis of the effect of
Deepthy Kavungal   +5 more
wiley   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

open access: yesAdvanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang   +21 more
wiley   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

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