Results 71 to 80 of about 15,446,480 (251)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MULTIPLICACIÓN Y TUBERIZACIÓN in vitro DE ÑAME (Dioscorea alata L.) EN SISTEMA DE INMERSIÓN TEMPORAL MULTIPLICATION AND in vitro TUBERIZATION OF YAM (Dioscorea alata L.) IN TEMPORARY IMMERSION SYSTEM

Revista Facultad Nacional de Agronomía Medellín, 2007
Se realizó la estandarización de la multiplicación y tuberización in vitro de ñame (Dioscorea alata L.) utilizando el sistema de inmersión temporal conocido como RITA®.
Robinson Salazar Díaz, Rodrigo Alberto Hoyos Sánche   +1 more
doaj  

Analysis of Immersion Timeliness for Soiland Its Application in Slope Stability of Port

Renmin Zhujiang, 2020
Immersion timeliness of sand-mudstone mixture is an important basis for the stabilityanalysis of slopes in mountainous portsduring the water level fluctuation process.
WU Xiao
doaj  

Evaluation of static tensile strength and fatigue strength degradation of plain woven CFRP laminates under seawater immersion

Nihon Kikai Gakkai ronbunshu, 2019
Carbon fiber reinforced plastics (CFRPs) are widely used as components of marine structures. Thus, it is important to understand the degradation of the mechanical properties and its mechanism under seawater immersion.
Shuhei KOSHIMA, Norihiro KAJII, Atsushi HOSOI, Hiroyuki KAWADA   +3 more
doaj   +1 more source

Impact of a cultural immersion experience on high school students' perceptions of self and identity [PDF]

, 2012
Counseling Program Research Project. 2012. Master of Science in Education-Counseling--University of Wisconsin-River Falls. Counseling and School Psychology Department. 48 leaves.
Herman, Benjamin
core  

Habituation of the Cold Shock Response May Include a Significant Perceptual Component [PDF]

, 2014
Introduction: Accidental immersion in cold water is a risk factor for many occupations. Habituation to cold-water immersion (CWI) is one practical means of reducing the cold shock response (CSR) on immersion.
Barwood, Martin J., Wagstaff, Christopher R. D., Wagstaff, Christopher, Corbett, Jo, Barwood, Martin   +4 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

The impact of contextualization on immersion in healthcare simulation [PDF]

, 2016
The aim of this paper is to explore how contextualization of a healthcare simulation scenarios impacts immersion, by using a novel objective instrument, the Immersion Score Rating Instrument.
Mikael Johannesson, Johannesson, Mikael, Engström, Henrik,, Lundberg, Lars, Sterner, Anders,, Andersson Hagiwara, Magnus,, Backlund, Per,, Maurin Söderholm, Hanna, Hanna Maurin Söderholm, Anders Sterner, Lars Lundberg, Lebram, Mikael, Lebram, Mikael,, Maurin Söderholm, Hanna,, Magnus Andersson Hagiwara, Backlund, Per, Mikael Lebram, Engström, Henrik, Andersson Hagiwara, Magnus, Per Backlund, Sterner, Anders, Henrik Engström, Johannesson, Mikael,, Lundberg, Lars,   +23 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source