Results 91 to 100 of about 4,903,889 (243)

The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer [PDF]

, 2021
Nick van Dijk, Alberto Gil-Jimenez, Karīna Siliņa, Maurits L. van Montfoort, Sarah Einerhand, Lars Jonkman, Charlotte S. Voskuilen, Dennis Peters, Joyce Sanders, Yoni Lubeck, Annegien Broeks, Erik Hooijberg, Daniël J. Vis, Maries van den Broek, Lodewyk F.A. Wessels, Bas W.G. van Rhijn, Michiel S. van der Heijden   +16 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Effects of Compound Feed Attractants on Growth Performance, Feed Utilization, Intestinal Histology, Protein Synthesis, and Immune Response of White Shrimp (Litopenaeus Vannamei) [PDF]

, 2022
Guilun He, Xin Chen, Qingtian Zeng, Wenbo Zhu, Zhengbang Chen, Beiping Tan, Shiwei Xie   +6 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Alpha-2-Macroglobulin, a Hypochlorite-Regulated Chaperone and Immune System Modulator [PDF]

, 2019
Jordan H. Cater, Mark R. Wilson, Amy R. Wyatt   +2 more
openalex   +1 more source

Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma [PDF]

, 2020
Shamik Mitra, Martin Lauss, Rita Cabrita, Jiyeon Choi, Tongwu Zhang, Karolin Isaksson, Håkan Olsson, Christian Ingvar, Ana Carneiro, Johan Staaf, Markus Ringnér, K. Nielsen, Kevin M. Brown, Göran Jönsson   +13 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Development of [18F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology

Nature Communications
Aggregated TDP-43 is a hallmark of frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), and limbic-predominant age-related TDP-43 encephalopathy (LATE), and a common co-pathology in other neurodegenerative diseases.
Efthymia Vokali, Elodie Chevalier, Nicolas Dreyfus, Dorian Charmey, Tania Melly, Jacqueline Kocher, Monisha Ratnam, Andreia M. Serra, Thomas Jaquier, Christophe Delgado, Myriam Ravache, Carlo Scialò, Sara Cappelli, Heiko Kroth, Francesca Capotosti, Ruth Luthi-Carter, Tariq Afroz, Madiha Derouazi, Cristian C. Constantinescu, Harro Seelaar, Emanuele Buratti, Peter T. Nelson, Magdalini Polymenidou, Andrea Pfeifer, Marie Kosco-Vilbois, Tamara Seredenina   +25 more
doaj   +1 more source

DNA damage-induced immune response: Micronuclei provide key platform [PDF]

, 2017
Nelson O. Gekara
openalex   +1 more source

Identification of key genes and novel immune infiltration-associated biomarkers of sepsis [PDF]

, 2020
Chao Xu, Jianbo Xu, Ling Lu, Wendan Tian, Jinling Ma, Meng Wu   +5 more
openalex   +1 more source