Results 301 to 310 of about 128,938 (315)

Unraveling Alveolar Fibroblast and Activated Myofibroblast Heterogeneity and Differentiation Trajectories During Lung Fibrosis Development and Resolution in Young and Old Mice

open access: yesAging Cell, EarlyView.
Model of LIF‐to‐aMYF reversible switch during fibrosis formation and resolution in old mice. The main contributors during fibrosis formation to Cthrc1+ aMYF are Acta2+ LIFhigh alveolar fibroblasts. During fibrosis resolution, Cthrc1+ aMYF differentiate back to the LIFhigh (please write "high" in superscript) alveolar fibroblasts cluster.
Arun Lingampally   +18 more
wiley   +1 more source

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians

open access: yesAging Cell, EarlyView.
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien   +11 more
wiley   +1 more source

Against all odds: The road to success in the development of human immune reconstitution mice. [PDF]

open access: yesAnimal Model Exp Med
Bin Y   +9 more
europepmc   +1 more source

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Immune Reconstitution Inflammatory Syndrome in a Patient With Cutaneous Leishmaniasis and HIV: A Diagnostic Challenge for Clinicians Caring for a Migrant Population in the United States. [PDF]

open access: yesOpen Forum Infect Dis
De La Hoz A   +10 more
europepmc   +1 more source

Immune reconstitution inflammatory syndrome-associated lymphoma: A retrospective Brazilian cohort. [PDF]

open access: yesEJHaem
Vargas JC   +11 more
europepmc   +1 more source

HIV-Induced Thymic Insufficiency and Aging-Related Immunosenescence on Immune Reconstitution in ART-Treated Patients. [PDF]

open access: yesVaccines (Basel)
Guedes MCS   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy