Results 151 to 160 of about 27,563 (247)
ABSTRACT Introduction Whether retinoids and carotenoids impact on graft‐versus‐host disease (GVHD) following allogeneic stem cell transplantation (ASCT) is unknown. Methods We conducted a 1:1 randomized controlled trial with extracorporeal photopheresis for GVHD‐prophylaxis as the intervention.
Per Ole Iversen +5 more
wiley +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Tuberculosis-associated immune reconstitution inflammatory syndrome in a non-immunocompromised patient. [PDF]
Angelopoulos V +8 more
europepmc +1 more source
CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang +36 more
wiley +1 more source
Hepatosplenic Tuberculosis Mimicking Metastatic Malignancy and Immune Reconstitution Inflammatory Syndrome (IRIS) in an HIV-Positive Patient. [PDF]
Maldonado JP +3 more
europepmc +1 more source
Inflammation, Immunity, and Cardiovascular Diseases
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo +8 more
wiley +1 more source
Thalidomide as an Adjunctive Therapy for HIV-Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome: A Case Series. [PDF]
Lee-Jones S +5 more
europepmc +1 more source
ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai +6 more
wiley +1 more source
ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier +7 more
wiley +1 more source
Grave's disease as a manifestation of immune reconstitution inflammatory syndrome in an HIV-infected child on highly active antiretroviral therapy: A case report. [PDF]
Haile AM +5 more
europepmc +1 more source

