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Introduction to the Immune System

2013
The immune system in a broad sense is a mechanism that allows a living organism to discriminate between "self" and "non-self." Examples of immune systems occur in multicellular organisms as simple and ancient as sea sponges. In fact, complex multicellular life would be impossible without the ability to exclude external life from the internal ...
McComb, S.   +3 more
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Innate Immunity in the Mucosal Immune System

Current Pharmaceutical Design, 2006
The mucosal immune system is equipped with unique innate and acquired defense mechanisms which provide a first line of protection against ingested and inhaled infectious agents. Peyer's patches (PPs) and nasopharynx-associated lymphoid tissue (NALT) have been shown to be important inductive sites for the initiation of the acquired phase of antigen ...
Tomonori, Nochi, Hiroshi, Kiyono
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The immune system in the elderly

Immunologic Research, 1999
The capability to cope with infectious agents and cancer cells resides not only in adaptive immune responses against specific antigens, mediated by T and B lymphocytes clonally distributed, but also in natural immune reactions. These innate defence mechanisms include chemotaxis, phagocytosis, natural cytotoxicity, cell interactions, and soluble ...
GINALDI, Lia   +5 more
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Aging and the immune system

Clinical Biochemistry, 1983
Information is presented on changes in the aging immune system. An analysis of separate streams of cellular aging in the inbred mouse is presented. It is demonstrated that there is extensive polymorphism in the aging of different types of executive and regulatory cell lines.
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The Hepatic Immune System

Critical Reviews™ in Immunology, 2002
The liver regulates T-cell homeostasis, induces T-cell tolerance, and supports intrahepatic T-cell responses against hepatotropic pathogens. Many data from clinical and preclinical systems provide supportive evidence for these diverse roles of the liver in modulating peripheral (systemic, mucosal, and intrahepatic) T-cell immunity.
Mary Jo, Wick   +2 more
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Aquaporins in Immune System

2023
Recent studies have shown that at least six aquaporins (AQPs), including AQP1, AQP3, AQP4, AQP5, AQP7, and AQP9, are expressed in immune system. These AQPs distribute in lymphocytes, macrophages, dendritic cells, and neutrophils, and mediate water and glycerol transportation in these cells, which play important roles in innate and adaptive immune ...
Yazhu, Quan, Bo, Kan, Baoxue, Yang
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Aging and the immune system

International Urology and Nephrology, 2008
Aging is associated with many physiological changes in a variety of organ systems. Nevertheless, considerable interest has centred on the possibility that age-related immunological changes may play a key "master" role in regulating many, if not all, subsequent events.
Reginald M, Gorczynski, Ender, Terzioglu
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The immune system and the nervous system

Journal of Neurology, 1983
The immune system may interfere with brain function. The central nervous system may also influence the activity of the immune system. The central nervous system is functionally protected by the blood-brain barrier. The central nervous system is functionally protected by the blood-brain barrier.
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Tachykinins in the Immune System

Current Drug Targets, 2006
Until recently, the mammalian tachykinins included substance P, neurokinin A and neurokinin B. Following the discovery of the fourth member of this family, hemokinin 1, a diverse group of novel tachykinins and tachykinin gene-related peptides have been identified in mammals.
Yu, Zhang   +3 more
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The immune memory of innate immune systems

International Immunology
Abstract Immune memory has long been considered a function specific to adaptive immune systems; however, adaptive immune memory alone has not fully explained the mechanism by which vaccines exert their protective effects against nontarget pathogens.
Yasuhiro Kato, Atsushi Kumanogoh
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