Results 131 to 140 of about 129,754 (292)

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

Journal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou, Ting Chen, Ying Huang, Huali Wang, Dahai He, Feng Wu, Yan Zhang, Lirui Kong   +7 more
wiley   +1 more source

Clinical Interpretation of Platelet Activation Marker sCLEC‐2 in Antiphospholipid Syndrome

Journal of Clinical Laboratory Analysis, EarlyView.
Soluble C‐type lectin‐like receptor 2 (sCLEC‐2), a marker of platelet activation, was evaluated in patients with antiphospholipid syndrome (APS). Plasma sCLEC‐2 levels and the sCLEC‐2/D‐dimer ratio were significantly elevated in APS compared with other collagen diseases and healthy controls.
Risa Kaneshige, Yukari Motoki, Kiyoshi Ichihara, Junzo Nojima   +3 more
wiley   +1 more source

Secondary immune thrombocytopenic purpura with renal cell carcinoma

IJU Case Reports, 2019
Introduction Several types of cancers are reported to induce secondary immune thrombocytopenia resembling immune thrombocytopenic purpura‐like syndrome. However, renal cell carcinoma‐induced immune thrombocytopenic purpura is an extremely rare phenomenon.
Shigeaki Nakazawa, Masataka Kawamura, Kosuke Nakano, Norichika Ueda, Hidefumi Kishikawa, Hirokazu Kashiwagi, Motohide Uemura, Ryoichi Imamura, Kenji Nishimura, Norio Nonomura   +9 more
doaj   +1 more source

Oral Cryptococcosis due to Naganishia diffluens in a Patient With Thalassemia: A Case Report and a Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh, Zeynab Haseli, Javad Javidnia, Mahdi Abastabar, Eisa Nazar, Hosein Jalali, Mohamad Taghi Hedayati, Hossein Karami, Mohsen Nosratabadi, Lotfollah Davoodi, Seyyed Reza Aghili, Maryam Moazeni, Iman Haghani, Hamid Badali   +13 more
wiley   +1 more source

Macrophage modulation in activation process induced immune thrombocytopenia

Universa Medicina
The immune system operates like an orchestra that harmoniously maintains the homeostasis balance while protecting from external or internal pathogens attack.
Mahdaleny Mahdaleny, Arleni Bustami, Febriana Catur Iswanti   +2 more
doaj   +1 more source

Anesthesia for cystotomy in a dog with pancreatitis and a portosystemic shunt [PDF]

, 2010
A 21-month-old Cocker spaniel with a portosystemic shunt, a moderate thrombocytopenia and a history of pancreatitis, was anesthetized for a cystotomy to remove bladder polyps and stones.
Brearley, JC, Gasthuys, Frank, Schauvliege, Stijn, Seymour, C   +3 more
core   +1 more source

The “5L” framework of diagnostic reasoning: A stepwise scaffold to support clinician educators

Journal of Hospital Medicine, EarlyView.
Abstract Diagnostic reasoning (DR) is a core clinical skill, yet its teaching remains variable. We introduce the “5L” framework as a bedside teaching scaffold that gives educators and learners a shared, stepwise set of prompts for DR during individual encounters. By asking, “What's Lethal? What's Likely? What's Logical? What's Lurking?
Olivia Brumfield, Amal Mohamed, Shuhan He, Cory Rohlfsen   +3 more
wiley   +1 more source

Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura : A Single Technology Appraisal [PDF]

, 2008
Evidence Review Group (ERG) final report for the National Institute for Health and Clinical ExcellencePublisher ...
Boyers, Dwayne, Crowther, M, Fraser, Cynthia Mary, Jenkinson, David James, Jia, Xueli, Mowatt, Graham   +5 more
core  

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source