Results 51 to 60 of about 129,754 (292)

Research Progress on Mechanism of Tumor-Associated Immune Thrombocytopenia

Zhongliu Fangzhi Yanjiu
Thrombocytopenia is a common complication during the treatment of malignant tumors. It can lead to insufficient doses of chemotherapy drugs or delayed chemotherapy, shorten patients’ survival time, and affect prognosis.
Guimin LIU, Huimin ZHU, Zhiyong CHENG, Wei QIN   +3 more
doaj   +1 more source

Optimized gating and reference ranges of reticulated platelets in dogs for the Sysmex XT-2000iV [PDF]

, 2016
Background: Canine reticulated platelets (r-PLTs) i.e., juvenile PLTs reflecting thrombopoiesis can be measured automatically with the hematology analyzer Sysmex XT-2000iV using manual gating options.
Bauer, Natali, Ginder, Melanie, Johannes, Sigrid, Moritz, Andreas, Oellers, Dana E., Pernecker, Iris   +5 more
core   +2 more sources

Bevacizumab-induced immune thrombocytopenia in an ovarian cancer patient with mixed connective tissue disease: case report and literature review

Frontiers in Immunology
Drug-induced immune thrombocytopenia is an adverse reaction marked by accelerated destruction of blood platelets. In cancer therapy, thrombocytopenia has many other causes including bone marrow suppression induced by chemotherapeutic agents, infection ...
Yunting Zhang, Fanchun Yang, Jining Wang, Hui Fu, Fuming Shen, Jie Liu, Dongjie Li   +6 more
doaj   +1 more source

Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]

, 2008
Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW, Beare NA, Calman Alexander MacLennan, Georges Emile Grau, Gerardin P, Israels SJ, Lewallen S, MacPherson GG, Malcolm Edward Molyneux, Mavuto Mukaka, Maxwell Kanjala, Ockenhouse CF, Samuel Crocodile Wassmer, Silamut K, Terrie Taylor, Thomas S, Udomsangpetch R, Wassmer SC, Yipp BG   +18 more
core   +1 more source

Rapid onset severe thrombocytopenia following reexposure to piperacillin-tazobactam: report of two cases and review of the literature

Platelets, 2018
Pipercillin-tazobactam is a frequently used antibiotic that has a broad spectrum of antibacterial activity. The development of severe thrombocytopenia following the use of piperacillin-tazobactam is unusual.
Musa Alzahrani, Ibrahim Alrumaih, Fahad Alhamad, Ahmed Abdel Warith   +3 more
doaj   +1 more source

Vaccine-induced thrombosis and thrombocytopenia (VITT); Exploring the unknown

Journal of Family Medicine and Primary Care, 2022
Vaccination is supposed to be the most reliable means to end the COVID 19 pandemic, but recently there have been reports of thrombosis and thrombocytopenia in patients receiving the vaccine especially ChAdOx1 nCoV-19 (AstraZeneca University of Oxford and
Ashok Sunder, Sudip Saha, Sangita Kamath, Manish Kumar   +3 more
doaj   +1 more source

Platelets at the vascular interface [PDF]

, 2018
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Bergmeier, Wolfgang, Stefanini, Lucia
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

MIF-mediated hemodilution promotes pathogenic anemia in experimental African trypanosomosis [PDF]

, 2016
Animal African trypanosomosis is a major threat to the economic development and human health in sub-Saharan Africa. Trypanosoma congolense infections represent the major constraint in livestock production, with anemia as the major pathogenic lethal ...
Beschin, Alain, Bieniasz-Krzywiec, Pawel, Brys, Lea, Bucala, Richard, Caljon, Guy, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Leng, Lin, Magez, Stefan, Mazzone, Massimiliano, Odongo, Steven, Sparkes, Amanda, Stijlemans, Benoît, Van Den Abbeele, Jan, Van Ginderachter, Jo A, Vanbekbergen, Nele, Vansintjan, Liese   +17 more
core   +5 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source