Results 171 to 180 of about 26,471 (221)

Immune Thrombocytopenic Purpura

New England Journal of Medicine, 2002
Immune thrombocytopenic purpura, which may lead to bleeding, is typically caused by antibodies directed against the platelet glycoprotein IIb/IIIa complex. Since the management of the disorder is different for children and adults, the authors of this up-to-date review provide separate sections on the two age groups.
Douglas B, Cines, Victor S, Blanchette
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Immune Thrombocytopenic Purpura

Hematology/Oncology Clinics of North America, 2007
Immune thrombocytopenic purpura (ITP) is an autoantibody-mediated thrombocytopenic disorder in which accelerated destruction of platelets occurs; platelet production may also be impaired by these antibodies. ITP is characterized by mucocutaneous bleeding. Rarely, more severe hemorrhages, such as intracranial hemorrhage, may occur. Traditional therapies,
Bethan, Psaila, James B, Bussel
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Immune thrombocytopenic purpura

The Indian Journal of Pediatrics, 2008
Immune thrombocytopenic purpura (ITP) is the commonest cause of sudden onset thrombocytopenia in a healthy child. The condition is frequently preceded by a viral infection. The hematological parameters are essentially normal except a low platelet count. Bone marrow examination is not routinely indicated except in specific situations.
V, Gupta, V, Tilak, B D, Bhatia
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Immune Thrombocytopenic Purpura ITP

Vox Sanguinis, 1998
AbstractImmune thrombocytopenic purpura ITP is characterized by early platelet destruction due to an unbalanced immune response. In acute ITP, a transient increase of HLA‐DR molecules has been detected while in individuals with chronic ITP, in addition, increased serum concentrations of IL‐2 and other cytokines reflecting in vivo T‐cell activation have
P, Imbach, T, Kühne
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Secondary immune thrombocytopenic purpura

Current Opinion in Hematology, 2007
The American Society of Hematology and British Committee for Standards in Haematology guidelines for the diagnosis and management of immune thrombocytopenic purpura focused entirely on primary disease, and secondary forms were not addressed. The guidelines did not address thrombocytopenia resulting from autoimmune disorders or chronic infections such ...
Howard A, Liebman, Roberto, Stasi
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Immune thrombocytopenic purpura

Pathology, 2010
The disease that was formerly termed idiopathic thrombocytopenia (ITP), is becoming far better understood, so much so that the same acronym has been reworked, to mean immune thrombocytopenia. Recent progress using murine models of the disease has shed new insights into the mechanisms of platelet destruction (both B and T cell mediated), and have lead ...
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Immune thrombocytopenic purpura

Postgraduate Medicine, 1977
Idiopathic thrombocytopenia is one of the most common hematologic disorders. It has many causes, most of which precipitate an immunologic reaction that results in immune thrombocytopenic purpura. A systematic approach to diagnosis and therapy is important.
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Childhood immune thrombocytopenic purpura

Blood Reviews, 2002
Childhood immune thrombocytopenic purpura (ITP) is acute and generally seasonal in nature, suggesting that infectious or environmental agents may trigger the immune response to produce platelet-reactive autoantibodies 4 to 8 weeks following an infection.
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Immune thrombocytopenic purpura.

The Medical clinics of North America, 1980
ITP is a hemorrhagic disorder in which thrombocytopenia is associated with increased peripheral destruction of platelets. It is a syndrome of different diseases, all of which have in common shortened platelet survival owing to the presence of an antiplatelet antibody. Most cases are secondary to an identifiable etiologic agent.
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