Results 11 to 20 of about 54,639 (294)

Daratumumab for immune thrombotic thrombocytopenic purpura [PDF]

Blood Advances, 2022
Abstract Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy. It is caused by a severe ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motifs, 13) deficiency due to circulating autoantibodies, and is associated with significant morbidity and mortality.
Van den Berg, Jana, Kremer Hovinga, Johanna A, Pfleger, Claudia, Hegemann, Inga, Stehle, Gregor Thomas, Holbro, Andreas, Studt, Jan-Dirk   +6 more
openaire   +5 more sources

Post-Partum Thrombotic Thrombocytopenic Purpura (TTP) in a Patient with known Idiopathic (Immune) Thrombocytopenic Purpura: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background Incidences of immune thrombocytopenic purpura occur in 1 in every 1000–10,000 pregnancies accounting for 3% of all thrombocytopenic pregnancies.
Naser Al-Husban, Oqba Al-Kuran
doaj   +2 more sources

Clinical factors and biomarkers predict outcome in patients with immune-mediated thrombotic thrombocytopenic purpura

Haematologica, 2019
Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves ...
Elizabeth M. Staley, Wenjing Cao, Huy P. Pham, Chong H. Kim, Nicole K. Kocher, Lucy Zheng, Radhika Gangaraju, Robin G. Lorenz, Lance A. Williams, Marisa B. Marques, X. Long Zheng   +10 more
doaj   +2 more sources

Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography [PDF]

Helicobacter, 2015
Idiopathic thrombocytopenic purpura (ITP) is typically a diagnosis of exclusion, assigned by clinicians after ruling out other identifiable etiologies. Since a report by Gasbarrini et al.
Beck, Paul L., Davis, Nicholas K., Fox, James G, Frydman, Galit   +3 more
core   +2 more sources

Immune thrombocytopenic purpura secondary to COVID‐19 vaccination: A systematic review

European Journal of Haematology, 2022
This systematic review aimed to retrieve patients diagnosed with de novo immune thrombocytopenic purpura (ITP) after COVID‐19 immunization to determine their epidemiological characteristics, clinical course, therapeutic strategies, and outcome.
A. Bidari, S. Asgarian, A. Pour Mohammad, Delaram Naderi, S. Anaraki, M. Gholizadeh Mesgarha, Mahya Naderkhani   +6 more
semanticscholar   +1 more source

Immune thrombocytopenic purpura after SARS‐CoV‐2 vaccine

British Journal of Haematology, 2021
In this paper, we describe the first case of immune thrombocytopenic purpura (ITP) after an adenovirus-based SARSCoV-2 vaccine. Some cases of ITP have already been described after the administration of both commercially available mRNA SARS-CoV-2 vaccines.
M. Candelli, E. Rossi, F. Valletta, V. De Stefano, F. Franceschi   +4 more
semanticscholar   +1 more source

Immune thrombocytopenic purpura and acute liver injury after COVID-19 vaccine

BMJ Case Reports, 2021
A 26-year-old woman was sent to the emergency room by her primary care physician for a new petechial rash and thrombocytopenia 2 weeks after receiving the Moderna mRNA-1273 SARS-CoV-2 vaccine. Her hospital course was complicated by transaminitis.
A. Hines, J. Shen, Coral Olazagasti, Shakil Shams   +3 more
semanticscholar   +1 more source

Vigilance regarding immune thrombocytopenic purpura after COVID-19 vaccine

Irish Journal of Medical Science, 2021
Introduction: Based on the severity of thrombocytopenia, patients with immune thrombocytopenic purpura (ITP) are at an increased risk of mucocutaneous or major bleeding.
V. Saudagar, S. Patil, S. Goh, S. Pothiawala   +3 more
semanticscholar   +1 more source

Epidemiology, treatment patterns, clinical outcomes, and disease burden among patients with immune‐mediated thrombotic thrombocytopenic purpura in the United States

Research and Practice in Thrombosis and Haemostasis, 2022
Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening thrombotic microangiopathy. Due to its rarity, epidemiology and real‐world outcomes data are scarce.
A. Adeyemi, Francesca Razakariasa, Alexandra Chiorean, Rui de Passos Sousa   +3 more
semanticscholar   +1 more source

Helicobacter pylori induced Immune Thrombocytopenic Purpura and perspective role of Helicobacter pylori eradication therapy for treating Immune Thrombocytopenic Purpura

AIMS Microbiology, 2021
Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterised by production of autoantibodies against platelet surface antigens. Recent studies have demonstrated a paramount association of ITP and Helicobacter pylori (H-pylori) infection ...
Arham Ihtesham, Shahzaib Maqbool, M. Nadeem, Muhammad Bilawal Abbas Janjua, Omaima Sundus, Ali Bakht Naqqash, Waleed Inayat Mohamed, Syed Turab Haider, Muhmmad Ahmad, Mir Ahmad Talha Mustafa, Hafiz Osama Mehboob   +10 more
semanticscholar   +1 more source