Results 261 to 270 of about 54,639 (294)

Is this immune thrombocytopenic purpura?

Archives of Disease in Childhood, 2008
When a well child comes to accident and emergency (A&E) with a history of sudden onset bruising, purpura and petechiae, and is found to have an isolated severe thrombocytopenia (TP), the diagnosis is usually obvious: acute immune thrombocytopenic purpura (ITP). But, could something more sinister be going on? Is ITP the correct diagnosis?
Jecko Thachil, Georgina W. Hall
openaire   +3 more sources

Immune Thrombocytopenic Purpura and Pregnancy

New England Journal of Medicine, 1982
Neonatal thrombocytopenia is a potentially life-threatening complication of immune thrombocytopenic purpura (ITP). We followed 23 pregnant women who had either a history of ITP (11 women) or clinically active disease (12 women) to delineate the factors responsible for neonatal thrombocytopenia.
Betsy Dusak, Michael T. Mennuti, Ann Tomaski, Douglas B. Cines, Alan D. Schreiber   +4 more
openaire   +4 more sources

Deaths and complications associated with the management of acute immune thrombotic thrombocytopenic purpura

Transfusion, 2020
The introduction of therapeutic plasma exchange (TPE) dramatically decreased mortality in patients with immune thrombotic thrombocytopenic purpura (iTTP).
M. Colling, Lova Sun, V. Upadhyay, Justine Ryu, Ang Li, L. Uhl, R. Kaufman, C. Stowell, W. Dzik, R. Makar, Pavan K Bendapudi   +10 more
semanticscholar   +1 more source

The geoepidemiology of immune thrombocytopenic purpura

Autoimmunity Reviews, 2010
First described in 1735 (Watson-Williams et al., 1958), immune-mediated platelet destruction is a phenomenon of protean associations that has historically varied in its definition. Recently, consensus guidelines were proposed for a standardized system of nomenclature that preserves the acronym "ITP" but encompasses a number of causes of immune-mediated
Sean Deane, M. Eric Gershwin, Suzanne S. Teuber   +2 more
openaire   +3 more sources

Splenectomy for Immune Thrombocytopenic Purpura

Archives of Surgery, 1981
Of 481 splenectomies performed at the University of Utah, Salt Lake City, 78 (16.2%) were for immune (idiopathic) thrombocytopenic purpura (ITP). The mean platelet count prior to therapy was 13,800/cu mm (range, 500 to 80,000/cu mm). All but two patients were initially treated with corticosteroids, and 58.2% responded with an increase in platelets ...
Bruce Cheson, Scott R. Petersen, Linda J. Cordell, Steven J. Mintz, Ralph C. Richards   +4 more
openaire   +3 more sources

Immune thrombocytopenic purpura

Pathology, 2010
The disease that was formerly termed idiopathic thrombocytopenia (ITP), is becoming far better understood, so much so that the same acronym has been reworked, to mean immune thrombocytopenia. Recent progress using murine models of the disease has shed new insights into the mechanisms of platelet destruction (both B and T cell mediated), and have lead ...
openaire   +3 more sources

Immune Thrombocytopenic Purpura in Infants

Archives of Pediatrics & Adolescent Medicine, 1994
Acute immune thrombocytopenic purpura (ITP) is a well-described illness in preschool and young school-aged children and is usually self-limited. It has been suggested that infants with acute ITP do not respond to conventional therapy as well as children between ages 1 and 8 years and are more likely to Comparison of Acute Immune Thrombocytopenic ...
James A. Whitlock, Neil J. Grossman, Jeffrey D. Hord   +2 more
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Immune Thrombocytopenic Purpura

Medical Clinics of North America, 1980
ITP is a hemorrhagic disorder in which thrombocytopenia is associated with increased peripheral destruction of platelets. It is a syndrome of different diseases, all of which have in common shortened platelet survival owing to the presence of an antiplatelet antibody. Most cases are secondary to an identifiable etiologic agent.
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Immune Thrombocytopenic Purpura ITP

Vox Sanguinis, 1998
AbstractImmune thrombocytopenic purpura ITP is characterized by early platelet destruction due to an unbalanced immune response. In acute ITP, a transient increase of HLA‐DR molecules has been detected while in individuals with chronic ITP, in addition, increased serum concentrations of IL‐2 and other cytokines reflecting in vivo T‐cell activation have
Paul Imbach, Thomas Kühne
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Immune thrombocytopenic purpura in pregnancy

Current Opinion in Hematology, 2007
This review assesses the need for revision of the present guidelines for immune thrombocytopenic purpura in pregnancy based on evidence-based data from published articles of relevance.The American Society of Hematology (ASH) and British Committee for Standards in Haematology (BCSH) guidelines indicate that at platelet counts below 70,000 or 80,000 ...
Terry Gernsheimer, Keith R. McCrae
openaire   +3 more sources