Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Catch-up immunisation for children in earthquake-affected areas of West Pasaman, Indonesia [PDF]
Children are a particularly vulnerable population when exposed to natural disasters and experience increased problems related to physical health, mental health and post-disaster learning.
Syawqi Rahmat +3 more
doaj +1 more source
Immunisation coverage in Australian Indigenous children : time to move the goal posts
Childhood immunisation coverage reported at 12 to
O'Grady, Kerry-Ann +5 more
core +1 more source
Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Current issues in immunisation (immunisation and asthma)
This is the first of an occasional series in Communicable Diseases Intelligence providing commentary on topical immunisation issues from the National Centre for Immunisation Research and Surveillance of Vaccine Preventive Diseases (NCIRS).
Peter B McIntyre +2 more
openaire +1 more source
Factors Affecting Childhood Immunisation in Bangladesh [PDF]
This study has examined the coverage of childhood immunisation and tried to identify the factors affecting the acceptance of immunisation practice among children in Bangladesh using the data from Bangladesh Demographic and Health Survey (BDHS) 93-94 ...
MD. Fasiul Alam +2 more
core
Inequalities in Childhood Immunisation in South Asia
Identifying the inequalities associated with immunisation coverage among children is crucial. We investigated the factors associated with complete immunisation among 12- to 23-month-old children in five South Asian countries: Afghanistan, Bangladesh ...
Nasser B. Ebrahim +5 more
core +1 more source
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Antenatal immunisation intentions of expectant parents: relationship to immunisation timeliness
Introduction: Most parents decide about their infant’s immunisations during pregnancy. We aimed to describe the immunisation intentions of pregnant women and their partners and identify associations between these intentions and immunisation timeliness ...
Bandara, D +10 more
core

