Results 111 to 120 of about 2,030,178 (334)
Журнал микробиологии, эпидемиологии и иммунобиологии, 2020 Introduction. The comprehensive assessment of the herd immunity to measles in Russia can be challenging, as Russian subject-related studies tend to focus on seroprevalence in various cohorts of different sizes.
Anna V. Nozdracheva +1 more
doaj +1 more source
How can veterinarians be interesting partners for organic dairy farmers? French farmers’ point of views [PDF]
, 2017 Organic dairy farmers must live up to the organic goal of ‘good health’ in respect the organic principles and regulation. Veterinarians could be the organic dairy farmers’ expected sparring partners in reaching this goal but have found difficulties to ...
Bareille, Nathalie +4 more
core +3 more sources
Advanced Science, EarlyView.A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim +4 more
wiley +1 more source
Advanced Science, EarlyView.NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang +8 more
wiley +1 more source
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Advanced Science, EarlyView.Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source
Vaccines in Current Culture: The HPV Vaccine Controversy [PDF]
, 2020 The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care.
Johnston, Alyssa
core +1 more source
Characterising two-pathogen competition in spatially structured environments [PDF]
, 2014 Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space structure of the ...
Colizza, Vittoria +5 more
core +4 more sources
Advanced Science, EarlyView.Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv +29 more
wiley +1 more source
Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
Advanced Science, EarlyView.CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
Advanced Science, EarlyView.Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source