Toxic mechanisms of amyloid oligomers and therapeutic strategies
Protein Science, Volume 35, Issue 4, April 2026.Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova +2 more
wiley +1 more source
Good Veterinary Practices for Managing the Colostral Period in Dairy Calves to Improve Their Immune Competence-A Systematic Review. [PDF]
Vet SciStancheva E, Penev T.
europepmc +1 more source
Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
Protein Science, Volume 35, Issue 4, April 2026.Abstract Oligomeric assemblies of amyloidogenic proteins, such as Aβ, tau, α‐synuclein, amylin, transthyretin, and TDP‐43, are increasingly recognized as key drivers of cellular dysfunction across a range of neurodegenerative and systemic disorders.
Magdalena I. Ivanova +2 more
wiley +1 more source
Strength and weakness of disease-induced herd immunity in networks. [PDF]
Proc Natl Acad Sci U S AHiraoka T +4 more
europepmc +1 more source
British Journal of Social Psychology, Volume 65, Issue 2, April 2026.Abstract Social psychology has long claimed neutrality in its explanations of collective behaviour, yet its foundational theories of crowds have repeatedly been co‐produced with institutions of authority and mobilized in the reactionary governance of social order.
Clifford Stott
wiley +1 more source
Measles Resurgence and the Fragility of Herd Immunity: Implications for Pediatric Infectious Disease Practice. [PDF]
J Pediatric Infect Dis SocHijano DR, Orenstein WA, Oliveira CR.
europepmc +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Optimizing influenza prevention: a systematic review of the cost-effectiveness of pediatric vaccination programs and vaccine types. [PDF]
Front Public HealthAksoy N +4 more
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What Goes First? Effects of Starvation on the Body Condition of a Neotropical Dung Beetle
Entomologia Experimentalis et Applicata, Volume 174, Issue 4, Page 321-328, April 2026.We investigated how prolonged starvation affects key physiological traits in the dung beetle Dichotomius bos. Prolonged starvation leads to significant reductions in body dry mass and fat reserves, while muscle mass remains unchanged. These findings indicate that dung beetles prioritize the maintenance of locomotor muscles while mobilizing stored ...
Leonardo Vilas‐Bôas M. P. de Cerqueira +5 more
wiley +1 more source