Results 221 to 230 of about 1,336,779 (318)

Correction for Green et al., The intestinal microbiota impacts nutritional immunity and resistance to <i>Acinetobacter baumannii</i> pneumonia. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Life-course immunology: reframing sex differences in the immune system to better understand women's health. [PDF]

Biol Sex Differ
Goulmamine S, Chew S.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Fueling the fire: aspartate deficiency primes and fuels STING activation. [PDF]

J Clin Invest
Jiang H, Wang W, Fu YX.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Immunogenicity and safety of a third and subsequent COVID-19 vaccine doses in patients with plasma cell dyscrasias. [PDF]

Blood Adv
Bhella S, Agbayani G, Hueniken K, Vijenthira A, Wilkin AM, Sebag M, Wang P, Hicks LK, Hay AE, Hosseini-Moghaddam SM, Assouline S, Balitsky A, Fraser G, Mangel J, Owen C, Reiman A, Sehn L, Sutherland H, Arnold C, McCurdy A, Reece D, Leite T, McCarthy E, Cooper C, Crawley AM, Langlois MA, Buchan CA, Allan D, Aw A, Betschel S, Bolotin S, Brandwein J, Bredeson C, Brooks J, Cheung M, Chu M, Gupta V, Kekre N, Kumar D, Moltzan C, Prica A, Stakiw J, Wright A, Baetz T, Dudebout J.   +44 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Mechanisms and therapeutic prospects of DNA methylation-mucosal innate immunity crosstalk in inflammatory bowel disease. [PDF]

Front Immunol
Zhang T, Ren Z, Kang Z, Pan Z, Wei G, Wang L, Man R, Peng J, Yu Y.   +8 more
europepmc   +1 more source

Innate Immunity and Acqired Immunity

Journal of Nippon Medical School, 2002
openaire   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source