Results 131 to 140 of about 584,176 (310)

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

KAP Study on Immunization of Children in a City of North India – A 30 Cluster Survey [PDF]

, 2008
Background: To determine the knowledge, attitude and practices about immunization among respondents of children aged 12-23 months.\ud Methods: A total of 510 respondents were interviewed in the urban slums of Lucknow district of India, using 30 cluster ...
Awasthi, Shally, Bhushan, Vidya, Kumar, Vishwajeet, Nath, Bhola, Singh , JV, Singh, SK   +5 more
core  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Introduction and roll-out of malaria vaccine in Sierra Leone: early lessons and experiences from the first 8 months of implementation

The Lancet Primary Care
Summary: Sierra Leone became the third country globally to roll-out the malaria vaccine, following Cameroon and Burkina Faso. As part of its comprehensive prevention and control measures against malaria, the Government of Sierra Leone, with the support ...
Desmond M Kangbai, MPhil, Edwin N Sesay, BPharm, Nella Clemens-Kangbai, MMed, Michael Jones, MPH, Andrew K Kemoh, MPH, Sallu Lansana, MPH, Joyce M Kallon, MSc, Edna G Samuels, BPharm, Jia B Kangbai, PhD, Tom Sesay, MSc   +9 more
doaj   +1 more source

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

Clinical Pharmacology &Therapeutics, EarlyView.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt, Patrick Souverein, Marloes Bazelier, Nicola Barclay, Antonella Delmestri, Miriam Sturkenboom, Daniel Prieto‐Alhambra, Helga Gardarsdottir, Olaf Klungel   +8 more
wiley   +1 more source

HBsAg-vectored DNA vaccines elicit concomitant protective responses to multiple CTL epitopes relevant in human disease. [PDF]

, 2008
Vaccines capable of controlling neoplastic and infectious diseases which depend on the cellular immune response for their resolution, have proven difficult to develop.
Allan Gould, Dekun Chen, Jacqueline Kattenbelt, Melanie Barnes, Michael Mather, Oscar Haigh, Robert R. Tindle, Scott Thomson   +7 more
core   +1 more source

Domestic and International Health Expenditure and Health and Healthcare Use: Evidence From Mozambique

Health Economics, EarlyView.
ABSTRACT Evidence on the relationship between public health expenditure and health is mixed and particularly scarce for low‐income countries. Existing studies overlook the subnational distribution of expenditure and rarely distinguish between sources and governance over funding.
Eliana Chavarría‐Pino, Laura Anselmi, Matt Sutton, Sérgio Chicumbe   +3 more
wiley   +1 more source

Associations between vaccination clinic factors and DTaP dropout in China: A cross-sectional study

Human Vaccines & Immunotherapeutics
Diphtheria, tetanus, and acellular pertussis combined vaccine (DTaP) dropout reflects negatively on the ability of a vaccination clinic to ensure children are fully vaccinated with recommended vaccines.
Jiakai Ye, Lei Cao, Yifan Song, Wenzhou Yu, Zhaonan Zhang, Li Li, Zundong Yin   +6 more
doaj   +1 more source

Recycling probability and dynamical properties of germinal center reactions

, 2001
We introduce a new model for the dynamics of centroblasts and centrocytes in a germinal center. The model reduces the germinal center reaction to the elements considered as essential and embeds proliferation of centroblasts, point mutations of the ...
Deutsch, Andreas, Meyer-Hermann, Michael, Or-Guil, Michal   +2 more
core   +2 more sources