Results 61 to 70 of about 584,176 (310)

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Research Trends of Vaccination-Related Systematic Reviews, 2011–2023: A Bibliometric Analysis

Publications
Systematic reviews (SRs) reflect the best available evidence for informing vaccination recommendations. This study presents a bibliometric analysis of vaccination-related SRs aiming to uncover research trends.
Antonia Pilic, Louise Henaff, Christoph A. Steffen, Hanna Helene Linß, Antonia Isabelle Dreyer, Madeleine Batke, Ole Wichmann, Vanessa Piechotta, Thomas Harder   +8 more
doaj   +1 more source

Changes in the epidemiology of hepatitis A in three socio-economic regions of China, 1990–2017

Infectious Diseases of Poverty, 2019
Background Hepatitis A (HepA) vaccination and economic transitions can change the epidemiology of HepA. China’s Gross Domestic Product (GDP) per capita was known to be inversely associated with the incidence of HepA, but a deeper understanding of the ...
Xiao-Jin Sun, Guo-Min Zhang, Rong-Jun Zhou, Hui Zheng, Ning Miao, Zun-Dong Yin, Fu-Zhen Wang   +6 more
doaj   +1 more source

The reform of the Italian legislation on childhood immunization [PDF]

, 2018
Upon the proposal of the Italian government, Law n. 191/2017 has been enacted, meant to considerably raise the number of mandatory vaccinations, while leaving several others merely "recommended" (non-mandatory).
Cocchiara, Rosario Andrea, La Torre, Giuseppe, Marinelli, Enrico, Montanari Vergallo, Gianluca, Zaami, Simona   +4 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

Hepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen, Yu‐Chia Su, Yee‐Ern Or, Chin‐Fu Cheng, John T. Kung   +4 more
wiley   +1 more source

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]

, 2015
BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony, Mandler, Markus, Mante, Michael, Masliah, Eliezer, Mattner, Frank, Patrick, Christina, Rockenstein, Edward, Santic, Radmila, Schmidhuber, Sabine, Schmidt, Walter, Schneeberger, Achim, Valera, Elvira, Weninger, Harald   +12 more
core   +2 more sources

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Evaluation of the impact of Shandong illegal vaccine sales incident on immunizations in China

Human Vaccines & Immunotherapeutics, 2018
A case of illegal vaccine sales in Shandong province, China, (hereinafter, the incident), which caused a lack of confidence among vaccination recipients and public panic, was uncovered in March 2016.
Lei Cao, Jingshan Zheng, Lingsheng Cao, Jian Cui, Qiyou Xiao   +4 more
doaj   +1 more source

A novel cellular pathway of antigen presentation and CD4 T cell activation in vivo [PDF]

, 2018
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Baz Morelli, Adriana, Benson, Robert A., Brewer, James M., Garside, Paul, Hayes, Alan J., Maraskovsky, Eugene, Meehan, Gavin R., Scales, Hannah E., Tomura, Michio, Walters, Anne, Watson, Emma   +10 more
core   +3 more sources