Results 51 to 60 of about 241,504 (343)
OBJECTIVE: To determine, over time, the rate and serotypes of pneumococci with reduced penicillin susceptibility obtained from children with invasive infection.
David Scheifele +14 more
doaj +1 more source
Iowa Immunization Program Annual Report 2011, February 20, 2012 [PDF]
The Bureau of Immunization is part of the Division of Acute Disease Prevention and Emergency Response (ADPER) at the Iowa Department of Public Health (IDPH).
core
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Kualitas Data Imunisasi Rutin Berdasarkan Metode Data Quality Self Assessment (Dqs) [PDF]
Reporting and Recording System on immunization in Indonesia have been faced with many difficulties. Data quality and accuracy are the main problem that can be found in Puskesmas, District Health Office and also in Provincial Health Office.
Tarigan, I. (Ingan)
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A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition [PDF]
The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodies ...
Aasa-Chapman, Marlén M. I. +23 more
core +6 more sources
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Children with primary immunodeficiency disorder (PID) are at higher risk of developing vaccine-associated paralytic poliomyelitis (VAPP) or vaccine-derived polioviruses (VDPV) infection when inadvertently expose to poliovirus vaccine, oral (OPV). A pilot
Ning Yao +12 more
doaj +1 more source
Efforts in Increasing Universal Child Immunization (Uci) Coverage of Kalirungkut Primary Health Center Surabaya [PDF]
Based on Surabaya District Health Office, in 2010-2012, there were only three Primary Health Centers that reach the target of UCI. Unfortunately, there were 15 other Primary Health Centers with 0% UCI coverage, one of them was Kalirungkut Primary Health ...
Arifiyanti, I. (Ika) +1 more
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The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
core +1 more source

