Results 51 to 60 of about 41,326 (253)

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen   +7 more
wiley   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong   +14 more
wiley   +1 more source

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic intestinal inflammation and impaired barrier function, for which effective long‐term therapies remain elusive. To address this challenge, we developed a novel nano‐vaccine that combines Prussian blue nanozymes (PBNZs) adjuvants with a ferritin carrier loaded with ...
Jingyi Sheng   +6 more
wiley   +1 more source

Health Extension Workers Knowledge and Associated Factors on Child Immunization in Bako Tibe, West Shewa, Oromia, Ethiopia: A Cross-Sectional Study

open access: yesJournal of Multidisciplinary Healthcare, 2021
Belachew Umeta,1 Biniyam Girma2 1School of Pharmacy, Department of Pharmaceutical Sciences, Institute of Health, Jimma University, Jimma, Oromia, Ethiopia; 2School of Pharmacy, Department of Pharmacology, Institute of Health, Jimma University, Jimma ...
Umeta B, Girma B
doaj  

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

THE PRELIMINARY DATA ON NATIONAL IMMUNIZATION SCHEDULE VACCINES COMBINED APPLICATION IN CHILDREN OF 6–7 YEARS OLD

open access: yesВопросы современной педиатрии, 2012
In the study, safety for influenza vaccine in combination with diphtheria vaccine, tetanus and measles vaccine, rubella vaccine, and epidemic parotitis in children of 6–7 years old was assessed.
I. V. Konovalov   +2 more
doaj   +1 more source

Online decision aids for contraceptive choices in women with chronic conditions: A systematic review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Women with chronic conditions face increased risks of unintended pregnancy and adverse maternal and perinatal outcomes. Tailored, online contraceptive decision aids might improve informed decision‐making and support reproductive health by promoting patient‐centered care in this population.
Begashaw Melaku Gebresillassie   +2 more
wiley   +1 more source

Clinical progress note: Hepatitis A virus

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Despite a decline in hepatitis A virus (HAV) incidence following vaccine introduction, HAV remains a public health concern in the United States. Recent multi‐state outbreaks have demonstrated that HAV can re‐emerge and highlight inequities in vaccine coverage or access, outbreak response, and in those with social or health risk factors ...
James M. McCluskey III   +2 more
wiley   +1 more source

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