Results 41 to 50 of about 6,254 (213)

Immunoadsorption therapy in autoimmune encephalitides [PDF]

Neurology Neuroimmunology & Neuroinflammation, 2016
It was hypothesized that in encephalitides with autoantibodies directed to CNS surface antigens an antibody-removing intervention might speed up recovery.The outcome of autoimmune encephalitis in 19 patients with antibodies against surface antigens (leucine-rich, glioma inactivated 1 [LGI1], n = 3; contactin-associated protein-2 [CASPR2], n = 4; NMDA ...
Dogan Onugoren, Müjgan, Golombeck, Kristin S., Bien, Corinna, Abu-Tair, Mariam, Brand, Marcus, Bulla-Hellwig, Michael, Lohmann, Hubertus, Münstermann, Dieter, Pavenstädt, Hermann, Thölking, Gerold, Valentin, Rainer, Wiendl, Heinz, Melzer, Nico, Bien, Christian G.   +13 more
openaire   +2 more sources

Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques

Frontiers in Immunology, 2021
The antiviral properties of broadly neutralizing antibodies against HIV are well-documented but no vaccine is currently able to elicit protective titers of these responses in primates.
Nuria Pedreño-Lopez, Brandon C. Rosen, Brandon C. Rosen, Walter J. Flores, Matthew J. Gorman, Thomas B. Voigt, Michael J. Ricciardi, Kristin Crosno, Kim L. Weisgrau, Christopher L. Parks, Jeffrey D. Lifson, Galit Alter, Eva G. Rakasz, Diogo M. Magnani, Mauricio A. Martins, David I. Watkins   +15 more
doaj   +1 more source

Clinical study on protein A immunoadsorption combined with glucocorticoid therapy for MOG antibody-associated optic neuritis

Yanke Xuebao
[Objective:] To investigate the clinical efficacy and safety of protein A immunoadsorption combined with glucocorticoid therapy in patients with myelin oligodendrocyte glycoprotein antibody-associated optic neuritis(MOG-ON).
DAI Yangyang, KUANG Zuying, YE Jinlong, PAN Mengqiu, ZHOU Lihua, LI Bo, WANG Zhanhang   +6 more
doaj   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

Neuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng, Siqi Tu, Yifan Zhou, Ruinan Shen, Xiaoyu Chen, Zhaozhao Cheng, Limei Wang, Yan Wu, Jie Lu, Shengjun Wang, Yan Xu, Wanhui Lin, Sheng Chen   +12 more
wiley   +1 more source

Protein-A immunoadsorption combined with immunosuppressive treatment in refractory primary Sjögren’s syndrome coexisting with NMOSD: a case report and literature review

Frontiers in Immunology
The treatment of primary Sjögren’s syndrome (pSS) coexisting with neuromyelitis optica spectrum disorder (NMOSD) using protein-A immunoadsorption combined with immunosuppressive therapy has rarely been reported.
Wei Fan, Wei Fan, Xuyan Chen, Pingping Xiao, Bo Wei, Yi Zhang, Jinmei Huang, Shufan Wu, Liangjing Lu   +8 more
doaj   +1 more source

ABO-incompatible kidney transplantation: Indian working group recommendations

Indian Journal of Transplantation, 2019
Expanding use of ABO-incompatible kidney transplant (ABOiKT) globally and in India demands harmonized protocols. With an aim to provide unified and standardized consensus for ABOiKT in Indian setting, a 14-member working group formulated this document on
A K Bhalla, B T Anil Kumar, Munish Chauhan, Pratik Das, Bhupendra Gandhi, Umapati Hegde, Tarun Jeloka, Manish Mali, Pranaw Kumar Jha, Ajay Kher, Kamal Kiran Mukkavilli, Raja Ramachandran, Vivekanand Jha   +12 more
doaj   +1 more source

Living Donor Kidney Transplantation in Patients With Donor-Specific HLA Antibodies After Desensitization With Immunoadsorption

Frontiers in Medicine, 2021
Due to the current organ shortage, living donor kidney transplantation is increasingly performed across HLA (human leukocyte antigen) or ABO antibody barriers. There is still uncertainty about the risk of antibody-mediated rejection (AMR) episodes, which
Florian Kälble, Caner Süsal, Caner Süsal, Luiza Pego da Silva, Claudius Speer, Louise Benning, Christian Nusshag, Lien Pham, Hien Tran, Matthias Schaier, Claudia Sommerer, Jörg Beimler, Arianeb Mehrabi, Martin Zeier, Christian Morath   +14 more
doaj   +1 more source

Allergen‐Functionalized Microfluidic Immunoadsorption Platform for Selective Depletion of Peanut‐Specific Antibodies From Whole Blood

Journal of Polymer Science, EarlyView.
We present a microfluidic immunoadsorption platform functionalized with a layer‐by‐layer (LbL) nanofilm composed of poly(diallyldimethylammonium chloride) (PDDA) and protein extract (PE) for selective capture of peanut‐specific antibodies directly from the whole blood obtained from a peanut allergy mouse model.
Hesaneh Ahmadi, Nur Hendri Wahyu Firdaus, Rutwik Joshi, Akhilesh Kumar Shakya, Wei Li   +4 more
wiley   +1 more source

Effects of immunoadsorption on α₁-AAB and blood pressure.

, 2013
(A) Ordinate shows neonatal cardiomyocyte spontaneous beating rate; abscissa shows response to immunoadorption performed on a representative patient. The α1-AAB activity decreased with every immunoadsorption with a total decrease in response over time ...
Dominik N. Muller (195402), Carsten Lindschau (375849), Stefan Verlohren (373445), Friedrich C. Luft (252646), Sabine Bartel (375844), Ralf Dechend (252651), Rainer Dietz (252649), Gerd Wallukat (252625), Hannelore Haase (375842), Volker Homuth (375845), Christoph Schroeder (341105), Ingo Morano (373459), Wolfgang Derer (375843), Marion Janczikowski (375847), Katrin Wenzel (252624), Florian Herse (252632), Herbert Schulz (30410), Norbert Hubner (20203), Peter Karczewski (313636)   +18 more
core   +1 more source

Evaluation of an ABO antibody immunoadsorption column for reduction of anti‐A and anti‐B isoagglutinin titers in group O platelet units

Transfusion, EarlyView.
Abstract Background Clinical guidelines recommend transfusing ABO‐identical platelets where possible. However, the short shelf life of platelets (5–7 days) and stock availability mean ABO‐nonidentical platelet transfusions are sometimes unavoidable. Minor ABO‐incompatible platelet transfusions carry a risk of hemolysis due to donor anti‐A/B antibodies,
Melanie J. Robbins, Susan Proffitt, Gillian Eastwood, Sian Huish, Kurt Nilsson, Rebecca Cardigan   +5 more
wiley   +1 more source