The Atypical and Suspicious for Malignancy Categories of the WHO Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Review of their Diagnostic Utility, Limitations, and Clinical Impact. [PDF]
ABSTRACT Background Fine‐needle aspiration biopsy (FNAB) is the preferred first‐line diagnostic tool for evaluating lymphadenopathy due to its minimally invasive nature and cost‐effectiveness. However, cytopathological interpretation of lymph node FNAB remains challenging because of the wide morphological spectrum of lymphoid lesions.
Cozzolino I +5 more
europepmc +2 more sources
Isolated Pleural Effusion as Presentation of a Large B-Cell Lymphoma: A Case Report and Diagnostic Considerations. [PDF]
A 79‐year‐old man presented with massive pleural effusion in which cytological examination revealed lymphoma cells without evidence of a solid tumor mass. Negative EBV in situ hybridization and negative HHV8 and HIV testing, combined with flow cytometric immunophenotyping and molecular findings, supported a diagnosis of fluid overload–associated large ...
Magalie VV +5 more
europepmc +2 more sources
Infectious Mononucleosis: An Uncommon Presentation of a Common Disease-a Case Report. [PDF]
Atypical infectious mononucleosis without pharyngitis may mimic malignancy; early EBV testing enables accurate diagnosis and prevents unnecessary invasive investigations. ABSTRACT Infectious mononucleosis (IM), caused by the Epstein–Barr virus (EBV), typically presents with fever, pharyngitis, and lymphadenopathy.
Moini M, Sheibani S, Ghazizadeh M.
europepmc +2 more sources
Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern-based approach. [PDF]
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Ehinger M +4 more
europepmc +2 more sources
Delayed Diagnosis of Sézary Syndrome: Lessons From a Psoriasiform Presentation. [PDF]
ABSTRACT Pruritic erythroderma is not always psoriasis. Resistant cases require a broad evaluation for cutaneous lymphoma. Early, timely diagnosis prevents disease progression, improves outcomes, and enhances quality of life, highlighting the need for re‐evaluation when conventional treatments fail.
Neupane S, Neupane A, Khan SA, Kausar H.
europepmc +2 more sources
An Unusual Presentation of Glandular Fever
Epstein-Barr virus (EBV) is an ubiquitous DNA herpesvirus with >90% of adults >40 years of age showing a serological response. While in their youth, primary EBV infection may pass unnoticed, young adults have a high incidence of infectious mononucleosis (
Dominic Worku, Li Hui Chang, Ian Blyth
doaj +1 more source
Abstract Background Angioimmunoblastic T‐cell lymphoma (AITL) is one of the most frequent peripheral T‐cell lymphomas (PTCL) in western countries. Skin involvement is common and may reveal the malignancy. Despite its frequency, skin involvement in AITL has been poorly described.
Romain Stammler +25 more
wiley +1 more source
Toxoplasma IgG Expressed in a Patient With Rosai-Dorfman Disease
Rosai-Dorfman Disease (RDD) is a rare benign disease characterized by sinus histiocytosis with massive lymphadenopathy. RDD can be differentiated from other types of histiocytosis by immunochemical analysis, as RDD is positive for S100.
Hung-Ju Liao, Ching-Wen Chiang
doaj +1 more source
Azathioprine‐induced lymphoma in a patient with Takayasu arteritis: A case report from Iraq
Azthioprine‐induced lymphoma. Key Clinical Message Azathioprine, used for vasculitis and connective tissue diseases, carries long‐term cancer risks. This case report raises awareness among healthcare providers about such risks and emphasizes the need for taking necessary precautions to avoid them while treating such diseases.
Nabaa Ihsan Awadh +5 more
wiley +1 more source
Aims Classic Hodgkin lymphoma (cHL) should be distinguished from its wide variety of histological mimics, including reactive conditions and mature B and T cell neoplasms. Thymus and activation‐related chemokine (TARC) is produced in extremely high quantities by the Hodgkin/Reed–Sternberg (HRS) tumour cells and is largely responsible for the attraction ...
Melvin Kilsdonk +4 more
wiley +1 more source

