Results 131 to 140 of about 4,533 (248)

Testosterone is positively related to the output of nematode eggs in male Alpine ibex (Capra ibex) faeces [PDF]

, 2007
Decristophoris, Paola M. A., von Hardenberg, Achaz, McElligott, Alan G.; id_orcid, von Hardenberg, A, McElligott, AG, Decristophoris, PMA   +5 more
core   +4 more sources

Synchronous Splenic and Intracerebral Abscesses in a Child

African Journal of Paediatric Surgery
Splenic abscess is a life-threatening condition, which is very rare in children. There is usually an infective focus or pre-disposing factors such as immunodeficiencies towards developing splenic abscesses.
Jideofor Okechukwu Ugwu, Adaobi Chiazor Emegoakor, Sylvester Okwuchukwu Obiechina, Nwanneka Ogechukwu Ugwu, Sunday Patrick Nkwerem   +4 more
doaj   +1 more source

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

Advanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li, Yu Zhang, Yu Chen, Lingyun He, Xian Shen, Weijian Sun, Hongbo Zhang   +6 more
wiley   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Effects of Dietary Fiber and Protein on Immunocompetence in White-footed Mice (Peromyscus leucopus)

, 2018
Diet quality is known to have an effect on immune responsiveness. To determine what aspects of diet affect immunity and what aspects of the immune system are most vulnerable, we tested the null hypothesis that diet quality has no effect on ...
Humphrey, Kyle, Schaumburg, Collin, Strong, Holly, Sutton, Natalie   +3 more
core   +1 more source

Pulmonary Aspergillus Nodule in an Immunocompetent Host: A Case Report

Clinical Case Reports
Aspergillus is a common fungal pathogen that typically causes severe infections in patients with compromised immunity. This report explores a rare case of a pulmonary Aspergillus nodule in an immunocompetent person without underlying conditions.
Ahmad Alikhani, Pooria Sobhanian, Mahla Hosseinzade, Shadi Shayesteh Azar, Farshad Naghshvar   +4 more
doaj   +1 more source

Males, Masculinity, and Immunity: A Test of the Immunocompetence Handicap Hypothesis in Fathead Minnows

, 2016
Mate selection by females typically favors males with more prominent sex specific traits or ornamentation. Previous studies have shown that the prominence of such male traits is positively correlated with androgen (e.g., testosterone) levels. An increase
Medders, Ali
core  

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source