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Primary Cutaneous Cryptococcosis: A Rare Masquerading Presentation of Cryptococcus Infection [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
The yeast, Cryptococcus is widely present in the environment. Its main portal of entry is the respiratory tract. Clinical and experimental evidences indicate that cryptococcosis is usually a reactivation of a dormant infection.
Tanisha Bharara   +3 more
doaj   +1 more source

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

open access: yesNature Biotechnology, 2023
A genetic method to block immune rejection of allogeneic cells is validated in monkeys. Genetic engineering of allogeneic cell therapeutics that fully prevents rejection by a recipient’s immune system would abolish the requirement for immunosuppressive ...
Xiaomeng Hu   +28 more
semanticscholar   +1 more source

Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer

open access: yesCancer Discovery, 2022
Pharmacologic inhibition of KrasG12D in therapy-refractory models of pancreatic ductal adenocarcinoma promotes deep tumor regressions with alterations in the tumor microenvironment.
Samantha B. Kemp   +22 more
semanticscholar   +1 more source

Human Herpesvirus 6 Encephalitis in Immunocompetent and Immunocompromised Hosts

open access: yesNeurology: Neuroimmunology & Neuroinflammation, 2021
Objective The aim of this study was to analyze the clinical, radiologic, and biological features associated with human herpesvirus 6 (HHV-6) encephalitis in immunocompetent and immunocompromised hosts to establish which clinical settings should prompt ...
G. Berzero   +16 more
semanticscholar   +1 more source

A case report of pneumonia due to non-tuberculous mycobacteria in an immunocompetent patient

open access: yesThe Pan African Medical Journal, 2021
Non-tuberculous mycobacteria are uncommon pathogens in immunocompetent individuals. We report an unusual case of pneumonia with pleural effusion caused by co-infection with two species of non-tuberculous mycobacteria in an immunocompetent man in Nigeria.
Olukemi Adekanmbi, Sulaiman Lakoh
doaj   +1 more source

Investigation of neglected protists Blastocystis sp. and Dientamoeba fragilis in immunocompetent and immunodeficient diarrheal patients using both conventional and molecular methods

open access: yesPLoS Neglected Tropical Diseases, 2021
Introduction The clinical significance of Blastocystis sp. and Dientamoeba fragilis in patients with gastrointestinal symptoms is a controversial issue. Since the pathogenicity of these protists has not been fully elucidated, testing for these organisms ...
Fakhriddin Sarzhanov   +6 more
semanticscholar   +1 more source

Primary tuberculous pyomyositis in an immunocompetent individual

open access: yesThe Journal of Association of Chest Physicians, 2021
Tuberculous pyomyositis is a rare complication of Mycobacterium tuberculosis infection. The reported incidence is around 1% of musculoskeletal tuberculosis.
Jayabal Pandiaraja, Arumugam Shalini
doaj   +1 more source

Rare Etiology of Odynophagia in a Female Adolescent

open access: yesCase Reports in Gastroenterology, 2021
Herpes esophagitis (HE) is a rare condition in immunocompetent adolescents. However, it commonly occurs as a primary infection in younger individuals. Herein, we report a 16-year-old female patient who had a history of fever for 5 days, odynophagia, and ...
Anastasios Koutsoumourakis   +3 more
doaj   +1 more source

Cytomegalovirus Hepatitis in Immunocompetent and Immunocompromised Hosts

open access: yesJournal of Clinical and Translational Hepatology, 2021
Human cytomegalovirus (HCMV) infection is common and affects between 40–100% of the worldwide population. However, the majority of cases are asymptomatic and when severe disease occurs, it is usually restricted to immunocompromised patients.
Teresa Da Cunha, George Y Wu
semanticscholar   +1 more source

Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model

open access: yesFrontiers in Immunology, 2020
Efficient T-cell targeting, infiltration and activation within tumors is crucial for successful adoptive T-cell therapy. Intravital microscopy is a powerful tool for the visualization of T-cell behavior within tumors, as well as spatial and temporal ...
Doreen Lau   +13 more
doaj   +1 more source

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